[D-Pro4,D-Trp7,9] Substance P

[D-Pro4,D-Trp7,9] Substance P (4-11)

产品活性：[D-Pro4,D-Trp7,9] Substance P (4-11) 是强效的 Substance P (HY-P0201) 拮抗剂。[D-Pro4,D-Trp7,9] Substance P (4-11) 降低血浆醛固酮 (ALDO) 浓度。

产品来源： www.medchemexpress.cn/d-pro4-d-trp7-9-substance-p-4-11.html

研究领域：Others

作用靶点：Others

In Vivo: [D-Pro4,D-Trp7,9] Substance P (4-11) inhibits the hypotensive effect of Substance P in anesthetized rats, the vasodilator effect in the rabbit perfused heart, relaxation induced by Substance P in dog carotid arteries contracted with noradrenaline, and stimulatory actions of Substance P in the guinea pig ileum and the guinea pig trachea.[D-Pro4,D-Trp7,9] Substance P (4-11) (0.3 nM/K/min; i.p. for 7 days) significantly decreases plasma aldosterone (ALDO) concentration and causes atrophy of adrenal zona glomerulosa (ZG) and its parenchymal cells.

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