- ￥264 - 1524
- MedChemExpress(MCE)
- 美国
- HY-112538
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Please store the product under the recommended conditions in the Certificate of Analysis.
- 英文名：
1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride
- 库存：
货期：询盘
- 供应商：
MedChemExpress LLC
- CAS号：
104113-71-5
- 规格：
5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 5 mg | 产品价格： | ￥264.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥393.0 |
| 规格： | 25 mg | 产品价格： | ￥679.0 |
| 规格： | 50 mg | 产品价格： | ￥1005.0 |
| 规格： | 100 mg | 产品价格： | ￥1524.0 |
1-(1-Naphthyl)piperazine hydrochloride
产品活性：1-1-Naphthylpiperazine hydrochloride (1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride) 是 Quipazine (HY-W028142) 的血清素能衍生物。1-1-Naphthylpiperazine hydrochloride 既是 5-HT1A 受体的激动剂，也是 5-HT2A 受体的拮抗剂。1-1-Naphthylpiperazine hydrochloride 可以诱导细胞凋亡 (apoptosis)。1-1-Naphthylpiperazine hydrochloride 可以预防免疫抑制和光致癌。
产品来源： www.medchemexpress.cn/1-1-naphthyl-piperazine-hydrochloride.html
研究领域：GPCR/G Protein | Neuronal Signaling | Apoptosis
作用靶点：5-HT Receptor | Apoptosis
In Vitro: 1-1-Naphthylpiperazine hydrochloride (50-300 μM) suppresses the melanoma cells MNT-1 with an IC50 is 163.6 μM, by inducing the cell cycle arrest at S-phase, cell apoptosis and ROS generation.1-1-Naphthylpiperazine hydrochloride (0-200 μM) regulates the expressions of related genes, which are associated with the UV-induced immunosuppression.
In Vivo: 1-1-Naphthylpiperazine hydrochloride (1 μM, i.p., single dose) promotes the DNA repair induced by UV radiation through the mechanism involving nucleotid excision repair(NER), which prevents the immune suppression and interferes the photocarcinogenesis in UVB exposed C57BL/6 mice.
相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Elesclomol | Rotenone | Etoposide | Ruxolitinib | SP600125 | Monomethyl auristatin E
产品活性：1-1-Naphthylpiperazine hydrochloride (1-NP hydrochloride; 1-Naphthylpiperazine hydrochloride) 是 Quipazine (HY-W028142) 的血清素能衍生物。1-1-Naphthylpiperazine hydrochloride 既是 5-HT1A 受体的激动剂，也是 5-HT2A 受体的拮抗剂。1-1-Naphthylpiperazine hydrochloride 可以诱导细胞凋亡 (apoptosis)。1-1-Naphthylpiperazine hydrochloride 可以预防免疫抑制和光致癌。
产品来源： www.medchemexpress.cn/1-1-naphthyl-piperazine-hydrochloride.html
研究领域：GPCR/G Protein | Neuronal Signaling | Apoptosis
作用靶点：5-HT Receptor | Apoptosis
In Vitro: 1-1-Naphthylpiperazine hydrochloride (50-300 μM) suppresses the melanoma cells MNT-1 with an IC50 is 163.6 μM, by inducing the cell cycle arrest at S-phase, cell apoptosis and ROS generation.1-1-Naphthylpiperazine hydrochloride (0-200 μM) regulates the expressions of related genes, which are associated with the UV-induced immunosuppression.
In Vivo: 1-1-Naphthylpiperazine hydrochloride (1 μM, i.p., single dose) promotes the DNA repair induced by UV radiation through the mechanism involving nucleotid excision repair(NER), which prevents the immune suppression and interferes the photocarcinogenesis in UVB exposed C57BL/6 mice.
相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Elesclomol | Rotenone | Etoposide | Ruxolitinib | SP600125 | Monomethyl auristatin E
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技术资料暂无技术资料 索取技术资料
1-(1-Naphthyl)piperazine1-萘酚哌嗪盐酸盐,104113-71-5
￥264 - 1524
