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- 2025年12月05日
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CB2 receptor agonist 6
产品活性：CB2 receptor agonist 6 (compound 70) 是一种 CB2R 激动剂，EC50 为162 nM。CB2 receptor agonist 6 对 CB1R 和 CB2R 的 IC50 值分别为 4.83 μM 和 0.88 μM。CB2 receptor agonist 6 是一种神经保护剂，可以用作神经系统疾病研究。
产品来源： www.medchemexpress.cn/cb2-receptor-agonist-6.html
研究领域：GPCR/G Protein | Neuronal Signaling
作用靶点：Cannabinoid Receptor
In Vitro: CB2 receptor agonist 6 (compound 70) (5 μM, 0/15/30/60 min) shows good metabolic stability
In Vitro .CB2 receptor agonist 6 (5 μM, 0/0.5/1/1.5/2 h) can activate CB2R
In Vitro and inhibit cAMP expression in mice and humans.CB2 receptor agonist 6 (0.01-10 μM, 90 min) shows selectivity to CB2R , with the values of Ki are 8.8 nM for CB1R and 0.89 nM for CB2R.
In Vivo: CB2 receptor agonist 6 (compound 70) (1 mg/kg, intraperitoneal injection, predetermined intervals 0.25/0.5/1/2/6/24 h) can significantly reverse the forgetting effect of scopolamine-induced amnesia murine model, and does not affect the spatial learning and memory ability of naive mice.
相关产品：AM251 | Rimonabant Hydrochloride | 2-Arachidonoylglycerol | Pregnenolone | JD-5037 | β-Caryophyllene | SR144528 | Anandamide | Taranabant | Leelamine | Olivetol | Olorinab | Yangonin | Synaptamide | S-Methoprene | AM281 | LY2828360 | Monlunabant | (±)-Ibipinabant | GW842166X | CB1 antagonist 4 | N-Oleoyl glycine | GW-405833 | MDA 19 | Org 27569 | Bay 59-3074
产品活性：CB2 receptor agonist 6 (compound 70) 是一种 CB2R 激动剂，EC50 为162 nM。CB2 receptor agonist 6 对 CB1R 和 CB2R 的 IC50 值分别为 4.83 μM 和 0.88 μM。CB2 receptor agonist 6 是一种神经保护剂，可以用作神经系统疾病研究。
产品来源： www.medchemexpress.cn/cb2-receptor-agonist-6.html
研究领域：GPCR/G Protein | Neuronal Signaling
作用靶点：Cannabinoid Receptor
In Vitro: CB2 receptor agonist 6 (compound 70) (5 μM, 0/15/30/60 min) shows good metabolic stability
In Vitro .CB2 receptor agonist 6 (5 μM, 0/0.5/1/1.5/2 h) can activate CB2R
In Vitro and inhibit cAMP expression in mice and humans.CB2 receptor agonist 6 (0.01-10 μM, 90 min) shows selectivity to CB2R , with the values of Ki are 8.8 nM for CB1R and 0.89 nM for CB2R.
In Vivo: CB2 receptor agonist 6 (compound 70) (1 mg/kg, intraperitoneal injection, predetermined intervals 0.25/0.5/1/2/6/24 h) can significantly reverse the forgetting effect of scopolamine-induced amnesia murine model, and does not affect the spatial learning and memory ability of naive mice.
相关产品：AM251 | Rimonabant Hydrochloride | 2-Arachidonoylglycerol | Pregnenolone | JD-5037 | β-Caryophyllene | SR144528 | Anandamide | Taranabant | Leelamine | Olivetol | Olorinab | Yangonin | Synaptamide | S-Methoprene | AM281 | LY2828360 | Monlunabant | (±)-Ibipinabant | GW842166X | CB1 antagonist 4 | N-Oleoyl glycine | GW-405833 | MDA 19 | Org 27569 | Bay 59-3074
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CB2 receptor agonist 6
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