NADH disodium,1949720-50-6

NADH disodium hydrate

产品活性：NADH disodium salt (Disodium NADH) hydrate 是一种口服有效的还原型辅酶。NADH disodium salt hydrate 还是 ADP-核糖基转移酶反应中的 ADP-核糖单元的供体和环状 ADP-核糖的前体。NADH disodium salt hydrate 在细胞的能量代谢过程中起到再生电子供体的作用，包括糖酵解，β-氧化和三羧酸 (TCA) 循环。

产品来源： www.medchemexpress.cn/nadh-disodium-hydrate.html

研究领域：Metabolic Enzyme/Protease

作用靶点：Endogenous Metabolite

In Vitro: NADH is unstable under acidic conditions but it is stable under alkaline conditions.NADH (0-1 mM; 0-12 h) increases NAD+ levels in various mammalian cell lines.NADH (1 mM; 24 h) causes low toxicity and protects cells from genotoxicity.

In Vivo: NADH (5 μmol/mouse; i.p.; once) increases urinary excretion of nicotinamide and its metabolites in mice.NADH (500 mg/kg; i.g.; once) promotes alcohol metabolism and prevents or ameliorates early liver injury caused by acute alcohol exposure in ethanol-loaded mice.NADH (1000 mg/kg; i.p.; once) enhances tissue NAD+ levels in male C57BL/6J mice.

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