- ￥1320 - 3930
- MedChemExpress(MCE)
- 美国
- HY-14669
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Store at room temperature 3 years
- 英文名：
Y-700; Piraxostat
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
1 mg/5 mg/10 mg
| 规格： | 1 mg | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥2690.0 |
| 规格： | 10 mg | 产品价格： | ￥3930.0 |
Niraxostat
产品活性：Niraxostat (Y-700; Piraxostat) 是一种口服有效的黄嘌呤氧化还原酶 (XOR) 抑制剂，可用于高尿酸血症和 XOR 可能涉及的其他疾病的研究。
产品来源： www.medchemexpress.cn/niraxostat.html
研究领域：Metabolic Enzyme/Protease
作用靶点：Xanthine Oxidase
In Vivo: Niraxostat (Y-700; 1 mg/kg) has high oral bioavailability (84.1%) and is almost not excreted through the kidneys. It is mainly eliminated through the liver.Niraxostat (Y- 700; 1-10 mg/kg; oral; single dose) dose-dependently reduces plasma urate levels in oxonate-treated rats .Niraxostat (Y-700 ; 0.3-3 mg/kg; Oral; Single dose) In normal rats, dose-dependently reduces urinary excretion of urate and allantoin while increasing excretion of hypoxanthine and xanthine.Pharmacokinetic Analysis of Niraxostat (Y-700) in normal ratsRouteDose (mg/kg)tmax (h)Cmax (μg/ml)AUC0-∞ (μg/h/ml)t1/2 (h) PO0.30.50.432.075.0 PO10.31.87.013.2 PO30.56.4930.312.7 IV1/3.978.342.5
相关产品：Baicalein | Allopurinol | Febuxostat | Benzbromarone | Lobetyolin | Oxypurinol | 6-Formylpterin | Phytic acid | Topiroxostat | Purpurogallin | Broussochalcone A | H-Tyr-Phe-OH | Myricetin 3-O-galactoside | 7,8,3′,4′-Tetrahydroxyflavone | Tigulixostat | URAT1&XO inhibitor 1 | 8-Azaadenine | Broussoflavonol F | Antioxidant agent-13 | Aurantiamide benzoate | Baicalein 6-O-glucoside | Ellagic acid 4-O-β-D-xylopyranoside | Eupatoriochromene | Febuxostat acyl glucuronide
产品活性：Niraxostat (Y-700; Piraxostat) 是一种口服有效的黄嘌呤氧化还原酶 (XOR) 抑制剂，可用于高尿酸血症和 XOR 可能涉及的其他疾病的研究。
产品来源： www.medchemexpress.cn/niraxostat.html
研究领域：Metabolic Enzyme/Protease
作用靶点：Xanthine Oxidase
In Vivo: Niraxostat (Y-700; 1 mg/kg) has high oral bioavailability (84.1%) and is almost not excreted through the kidneys. It is mainly eliminated through the liver.Niraxostat (Y- 700; 1-10 mg/kg; oral; single dose) dose-dependently reduces plasma urate levels in oxonate-treated rats .Niraxostat (Y-700 ; 0.3-3 mg/kg; Oral; Single dose) In normal rats, dose-dependently reduces urinary excretion of urate and allantoin while increasing excretion of hypoxanthine and xanthine.Pharmacokinetic Analysis of Niraxostat (Y-700) in normal ratsRouteDose (mg/kg)tmax (h)Cmax (μg/ml)AUC0-∞ (μg/h/ml)t1/2 (h) PO0.30.50.432.075.0 PO10.31.87.013.2 PO30.56.4930.312.7 IV1/3.978.342.5
相关产品：Baicalein | Allopurinol | Febuxostat | Benzbromarone | Lobetyolin | Oxypurinol | 6-Formylpterin | Phytic acid | Topiroxostat | Purpurogallin | Broussochalcone A | H-Tyr-Phe-OH | Myricetin 3-O-galactoside | 7,8,3′,4′-Tetrahydroxyflavone | Tigulixostat | URAT1&XO inhibitor 1 | 8-Azaadenine | Broussoflavonol F | Antioxidant agent-13 | Aurantiamide benzoate | Baicalein 6-O-glucoside | Ellagic acid 4-O-β-D-xylopyranoside | Eupatoriochromene | Febuxostat acyl glucuronide
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Niraxostat,206884-98-2
￥1320 - 3930
