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Cantharidic acid disodium
产品活性：Cantharidic acid disodium 是酸酐 Cantharidin 的水解产物，可诱导多种人类癌细胞凋亡 (apoptosis)。Cantharidic Acid disodium 是一种选择性蛋白磷酸酶 2 (PP2A) 和 PP1 抑制剂，IC50 值分别为 50 nM 和 600 nM。
产品来源： www.medchemexpress.cn/cantharidic-acid-disodium.html
研究领域：Metabolic Enzyme/Protease | Apoptosis
作用靶点：Phosphatase | Apoptosis
In Vitro: Cantharidic acid (0-20 μM; 24 h) markedly reduces cell viability, which is revealed by the upregulation of caspase activation in extrinsic and intrinsic apoptosis pathways as well as the upregulation of ERK1/2, p38, and JNK1/2 pathways.
In Vivo: Cantharidic acid (10 mg/kg; ip; once) causes extreme liver enlargement and congestion in mice. Hepatic glycogenolysis is increased as evidenced by elevations in blood glucose and hepatic glycogen phosphorylase levels and by corresponding reductions in hepatic glycogen content and glycogen synthase activity.
相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Elesclomol | Rotenone | Etoposide | Ruxolitinib | SP600125 | Cyclosporin A
产品活性：Cantharidic acid disodium 是酸酐 Cantharidin 的水解产物，可诱导多种人类癌细胞凋亡 (apoptosis)。Cantharidic Acid disodium 是一种选择性蛋白磷酸酶 2 (PP2A) 和 PP1 抑制剂，IC50 值分别为 50 nM 和 600 nM。
产品来源： www.medchemexpress.cn/cantharidic-acid-disodium.html
研究领域：Metabolic Enzyme/Protease | Apoptosis
作用靶点：Phosphatase | Apoptosis
In Vitro: Cantharidic acid (0-20 μM; 24 h) markedly reduces cell viability, which is revealed by the upregulation of caspase activation in extrinsic and intrinsic apoptosis pathways as well as the upregulation of ERK1/2, p38, and JNK1/2 pathways.
In Vivo: Cantharidic acid (10 mg/kg; ip; once) causes extreme liver enlargement and congestion in mice. Hepatic glycogenolysis is increased as evidenced by elevations in blood glucose and hepatic glycogen phosphorylase levels and by corresponding reductions in hepatic glycogen content and glycogen synthase activity.
相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Elesclomol | Rotenone | Etoposide | Ruxolitinib | SP600125 | Cyclosporin A
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Cantharidic acid disodium
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