- ￥1980
- MedChemExpress(MCE)
- 美国
- HY-126898
- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
1 mg
5-LO/mPGES-1-IN-1
产品活性：5-LO/mPGES-1-IN-1 (Compound 16) 是一种微粒体前列腺素 E2 合成酶-1 (mPGES-1) 和 5-脂氧合酶 (5-LO) 双重抑制剂，IC50 值分别为 0.3 和 0.4 μM。5-LO/mPGES-1-IN-1 具有抗炎活性。
产品来源： www.medchemexpress.cn/5-lo-mpges-1-in-1.html
研究领域：Metabolic Enzyme/Protease | Immunology/Inflammation
作用靶点：Lipoxygenase | PGE synthase
In Vivo: 5-LO/mPGES-1-IN-1 (10 mg/kg, intraperitoneally injected, pretreated 30 minutes before peritonitis induction) reduces vascular permeability and inflammatory cell infiltration in zymosan-induced mouse peritonitis models. Impaired cysteine-leukotriene and prostaglandin E2 levels.
相关产品：U-73122 | Oxidopamine hydrobromide | Zileuton | Wedelolactone | ML355 | Caffeic acid | Nordihydroguaiaretic acid | ML351 | Sinensetin | Psoralidin | AT-56 | Indirubin-3'-monoxime | Chebulagic acid | Cafestol | CAY10526 | Licofelone | Ethyl Caffeate | (S)-Flurbiprofen | MF63 | Dehydroevodiamine hydrochloride | 4',5-Dihydroxyflavone | Limaprost | Pectolinarigenin | Benzydamine hydrochloride | Zomepirac sodium salt | 15-LOX-1 inhibitor 1 | Cirsiliol | PF-4191834 | Zaloglanstat
产品活性：5-LO/mPGES-1-IN-1 (Compound 16) 是一种微粒体前列腺素 E2 合成酶-1 (mPGES-1) 和 5-脂氧合酶 (5-LO) 双重抑制剂，IC50 值分别为 0.3 和 0.4 μM。5-LO/mPGES-1-IN-1 具有抗炎活性。
产品来源： www.medchemexpress.cn/5-lo-mpges-1-in-1.html
研究领域：Metabolic Enzyme/Protease | Immunology/Inflammation
作用靶点：Lipoxygenase | PGE synthase
In Vivo: 5-LO/mPGES-1-IN-1 (10 mg/kg, intraperitoneally injected, pretreated 30 minutes before peritonitis induction) reduces vascular permeability and inflammatory cell infiltration in zymosan-induced mouse peritonitis models. Impaired cysteine-leukotriene and prostaglandin E2 levels.
相关产品：U-73122 | Oxidopamine hydrobromide | Zileuton | Wedelolactone | ML355 | Caffeic acid | Nordihydroguaiaretic acid | ML351 | Sinensetin | Psoralidin | AT-56 | Indirubin-3'-monoxime | Chebulagic acid | Cafestol | CAY10526 | Licofelone | Ethyl Caffeate | (S)-Flurbiprofen | MF63 | Dehydroevodiamine hydrochloride | 4',5-Dihydroxyflavone | Limaprost | Pectolinarigenin | Benzydamine hydrochloride | Zomepirac sodium salt | 15-LOX-1 inhibitor 1 | Cirsiliol | PF-4191834 | Zaloglanstat
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5-LO/mPGES1-IN-1,1492060-44-2
￥1980
