- ￥2650 - 4000
- MedChemExpress(MCE)
- 美国
- HY-157913
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
5 mg/10 mg
| 规格： | 5 mg | 产品价格： | ￥2650.0 |
|---|---|---|---|
| 规格： | 10 mg | 产品价格： | ￥4000.0 |
PKM2-IN-6
产品活性：PKM2-IN-6 (compound 7d) 是一种有效的和具有口服活性的 PKM2 抑制剂，IC50 值为 23 nM。PKM2-IN-6 诱导细胞凋亡 (apoptosis) 和细胞周期停滞在 G2 期。PKM2-IN-6 在 mRNA 水平降低 PKM1 和 PKM2 的表达。PKM2-IN-6 显示出抗癌活性，具有研究三阴性乳腺癌的潜力。
产品来源： www.medchemexpress.cn/pkm2-in-6.html
研究领域：Metabolic Enzyme/Protease | Apoptosis
作用靶点：Pyruvate Kinase | Apoptosis
In Vitro: PKM2-IN-6 (compound 7d) (0, 20, 40, 60, 80, 100 μM; 48 h) shows cytotoxicity with IC50s of 18.33, 47.00, 19.80 µM for COLO-205, A-549, MCF-7 cells, respectively.PKM2-IN-6 (14.38 μM; 48 h) induces apoptosis and cell cycle arrest at G2 phase.PKM2-IN-6 (14.38 μM; 24 h) reduces the PKM1 and PKM2 at the mRNA level.
In Vivo: PKM2-IN-6 (25, 50 mg/kg; p.o.; daily for 3 weeks) decreases the tumor volume and tumor weight in mice.
相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Elesclomol | Rotenone | Etoposide | Ruxolitinib | SP600125 | Monomethyl auristatin E
产品活性：PKM2-IN-6 (compound 7d) 是一种有效的和具有口服活性的 PKM2 抑制剂，IC50 值为 23 nM。PKM2-IN-6 诱导细胞凋亡 (apoptosis) 和细胞周期停滞在 G2 期。PKM2-IN-6 在 mRNA 水平降低 PKM1 和 PKM2 的表达。PKM2-IN-6 显示出抗癌活性，具有研究三阴性乳腺癌的潜力。
产品来源： www.medchemexpress.cn/pkm2-in-6.html
研究领域：Metabolic Enzyme/Protease | Apoptosis
作用靶点：Pyruvate Kinase | Apoptosis
In Vitro: PKM2-IN-6 (compound 7d) (0, 20, 40, 60, 80, 100 μM; 48 h) shows cytotoxicity with IC50s of 18.33, 47.00, 19.80 µM for COLO-205, A-549, MCF-7 cells, respectively.PKM2-IN-6 (14.38 μM; 48 h) induces apoptosis and cell cycle arrest at G2 phase.PKM2-IN-6 (14.38 μM; 24 h) reduces the PKM1 and PKM2 at the mRNA level.
In Vivo: PKM2-IN-6 (25, 50 mg/kg; p.o.; daily for 3 weeks) decreases the tumor volume and tumor weight in mice.
相关产品：MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | Tamoxifen | Y-27632 | LY294002 | Paclitaxel | Z-VAD-FMK | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | Actinomycin D | SB-431542 | 5-Fluorouracil | Bortezomib | Deferoxamine mesylate | Oxaliplatin | Trametinib | Sorafenib | Temozolomide | Gemcitabine | Decitabine | Mdivi-1 | Elesclomol | Rotenone | Etoposide | Ruxolitinib | SP600125 | Monomethyl auristatin E
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
PKM2-IN-6,771467-00-6
￥2650 - 4000
