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文献和实验In Vivo Models of Human Prostate Cancer Bone Metastasis
According to the American Cancer Society, adenocarcinoma of the prostate is the most common newly-diagnosed cancer in men and was the secondleading cause of cancer-related death in men more than 60 yr of age in the year 2000
Identification of Prostate Cancer-Associated MicroRNAs in Circulation Using a Mouse Model of Disease
fingerprints associated with that pathology. One strategy to minimize such heterogeneity is to employ genetically engineered mouse models of human cancer. Here, we describe a method to profile miRNAs in the serum of a mouse model of prostate cancer, TRansgenic
functions as an oncogenic protein in the progression of recurrent human prostate cancer. This chapter describes the use of antisense ODN to directly target cellular protein kinase C-epsilon as a potential chemotherapeutic agent for blocking the advance
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