- ￥8781.63
- ATCC
- KCSP.ATCC.CRL-2119
- 2025年10月02日
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文献和实验Ribozymes as a Novel Approach for the Treatment of Human Pancreatic carcinoma
), and the human immunodeficiency virus type 1 (10 ,14 ,15 ). Our Studies have previously demonstrated that anti-oncogene ribozymes effectively suppress the expression of targeted genes and result in the reversal of the malignant phenotype in human cancer cells
Ribozyme as an approach for growth suppression of human pancreatic cancer
of ribozyme targeting of the mutated K-ras oncogene in a human pancreatic carcinoma cell line. We evaluated the efficacy of an anti-K-ras hammerhead ribozyme targeted against GUU-mutated codon 12 of the K-ras gene in cultured pancreatic carcinoma cell lines
stages. The patients remain asymptomatic until late in the course of the disease. An excellent review of pancreatic carcinoma has appeared (2). Despite the progress made in our understanding of the biology of this cancer (3), the final outcome
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