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文献和实验Comparative Genomic Hybridization of Human Lung Cancer
Lung cancer is a highly aggressive neoplasm, a characteristic that is reflected by the multitude of genetic aberrations detectable on the chromosomal and molecular level. In order to understand these seemingly chaotic chromosomal alterations
Chemoprevention of Lung Cancer
and non steroidal anti-inflammatory drugs and cyclooxygenase-2 inhibitors for colon cancer“ (1 ). This somewhat pessimistic statement reflects the outcome of several clinical trials that examined whether human lung cancer could effectively be prevented
Mutations in the K-ras oncogene and mutations or deletions in the tumor suppressor gene p53 are the two most prevalent oncogenetic alterations in human lung cancer. Ras mutations occur primarily in lung adenocarcinomas and small numbers
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