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文献和实验PPAR/ Agonist Increases the Expression of PGE2 Receptor Subtype EP4 in Human Lung Carcinoma Cells
an important role in the effort to help extend its dismal 5-year survival rate (2 (PGE2 ), and the prostag-landin E2 receptor subtype, EP4, promote the growth and progression of human nonsmall cell lung carcinoma (NSCLC), the most common lung carcinoma
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
, there has been a concomitant change in the histologic type of lung cancer (4) . While SCLC has persisted at about 20%, adenocarcinoma has increased to 45% with declines in squamous cell and large cell carcinoma. Thun and colleagues (5) have suggested that these changes
Tumor Suppressor Genes in Lung Cancer
carcinoma (SCC), and large cell carcinoma (LC). SCLC is one of the most virulent forms of human cancer, characterized by early dissemination and aggressive clinical evolution as compared to NSCLC. The initial responsiveness of SCLC to anticancer drugs
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