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CD4 T-Cell Epitope Mapping

and H2-A and E in mice) for CD4+ T cells. However, a significant proportion of T cells recognize peptide antigens bound to nonclassical MHC class Ib molecules such as the human HLA-E (mouse analog Qa1) (4 ) and mouse H2-M3 (5 ). In addition, some T

Production of CD4+ and CD8+ T Cell Hybridomas

T cell hybridomas are very useful tools to investigate antigen presenting cell (APC) function. They were developed based on the fusion technology that led to monoclonal antibody section. Antigen-specific primary T cells are generated

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