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Glypican 3 Recombinant Rabbit

mAb(bsm-60006R)-50ul/100ul/25ul
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  • ¥800 - 2500
  • Bioss已认证
  • bsm-60006R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/25ul

    规格:50ul产品价格:¥1400.0
    规格:100ul产品价格:¥2500.0
    规格:25ul产品价格:¥800.0
    产品编号bsm-60006R
    英文名称Glypican 3 Recombinant Rabbit mAb
    中文名称磷脂酰基醇蛋白聚糖-3重组兔单抗
    英文别名GPC3; glypican3; glypican-3; Intestinal protein OCI-5; GTR2-2; MXR7.Intestinal protein OCI-5; GPC3_HUMAN.
    产品应用WB=1:500-2000, Flow-Cyt=1:20-100

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原A synthesized peptide derived from human Glypican 3
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    理论分子量65 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cancer > Tumor biomarkers

    Developmental Biology > Lineage specification > Mesoderm

    Signal Transduction > Cytoskeleton / ECM > HSPGs

    Stem Cells > Lineage Markers > Mesoderm

    亚细胞定位Cell membrane and Secreted, extracellular space.
    组织特异性Highly expressed in lung, liver and kidney.
    相似性Belongs to the glypican family.
    功能Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

     

    应用推荐稀释比例
    {WB}{1:500-2000}
    {Flow-Cyt}{1:20-100}

     

    产品细节图片1
    25 ug total protein per lane of various lysates (see on figure) probed with Glypican 3 monoclonal antibody, unconjugated (bsm-60006R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.

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