Sample:
Lane 1: U2os (Human) Cell Lysate at 30 ug
Lane 2: MG63 (Human) Cell Lysate at 30 ug
Lane 3: Huvec (Human) Cell Lysate at 30 ug
Lane 4: Hela (Human) Cell Lysate at 30 ug
Primary: Anti-BMP2 (bs-0514R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 60/45 kD
Observed band size: 60/45 kD
- ￥1180 - 2800
- Bioss
- bs-0514R
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-0514R |
| 英文名称 | BMP2 Rabbit pAb |
| 中文名称 | 骨形态发生蛋白2抗体 |
| 英文别名 | Bone morphogenetic protein 2; BMP 2; BMP 2A; BMP2A; BMP-2; BMP2_HUMAN. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human (Mouse, Rat, Dog, Pig, Cow, Rabbit) |
| 抗体来源 | Rabbit |
| 免疫原 | Recombinant human BMP2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 13/44 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Growth factors > TGF Cardiovascular > Angiogenesis > Growth Factors > TGF Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > Structures > Bone Signal Transduction > Growth Factors/Hormones > TGF Stem Cells > Neural Stem Cells > Extracellular Stem Cells > Signaling Pathways > TGF beta > Secreted |
| 亚基 | Homodimer; disulfide-linked. Interacts with SOSTDC1. Interacts with GREM2, RGMA, RGMB and RGMC. Interacts with ASPN. |
| 亚细胞定位 | Secreted. |
| 组织特异性 | Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine. |
| 相似性 | Belongs to the TGF-beta family. |
| 功能 | Induces cartilage and bone formation. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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文献和实验该产品被引用文献
[IF={{ 6.064 }}] {Yi-Xuan Wang. et al. MiR-20a promotes osteogenic differentiation in bone marrow-derived mesenchymal stem/stromal cells and bone repair of the maxillary sinus defect model in rabbits. FRONT BIOENG BIOTECH. 2023; 11: 1127908} {WB} {Human}
[IF={{ 5.4 }}] {Chaode Cen. et al.Construction of a 3D Degradable PLLA/β-TCP/CS Scaffold for Establishing an Induced Membrane Inspired by the Modified Single-Stage Masquelet Technique.ACS BIOMATERIAL SCIENCE & ENGINEERING.2025 Mar 10;11(3):1629-1645.} {IHC} {Rabbit}
[IF={{ 3.21 }}] {Ming-Zhi Huang. et al. Exosomes from artesunate-treated bone marrow-derived mesenchymal stem cells transferring SNHG7 to promote osteogenesis via TAF15-RUNX2 pathway. REGEN MED. 2022 Oct 02} {WB} {Mouse, Human}
[IF={{ 2.586 }}] {Yixin Xia. et al. Regulation of endothelial cells on the osteogenic ability of bone marrow mesenchymal stem cells in peri-implantitis. TISSUE CELL. 2023 Apr;81:102042} {WB} {Dog}
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BMP2 Rabbit pAb(bs-0514R)-50ul/100ul/200ul
￥1180 - 2800
