CD1c Recombinant Rabbit mAb(bsm-60660R)-50ul/100ul/25ul

CD1c Recombinant Rabbit mAb(bs

m-60660R)-50ul/100ul/25ul
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  • ¥800 - 2500
  • Bioss已认证
  • bsm-60660R
  • 2025年10月24日
  • 产品信息以Bioss网站为准
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    • 规格

      50ul/100ul/25ul

    规格:50ul产品价格:¥1400.0
    规格:100ul产品价格:¥2500.0
    规格:25ul产品价格:¥800.0
    产品编号bsm-60660R
    英文名称CD1c Recombinant Rabbit mAb
    中文名称T细胞表面糖蛋白CD1C重组兔单抗
    英文别名CD1c antigen; CD1C antigen c polypeptide; CD1c molecule; CD1C_HUMAN; Cortical thymocyte antigen CD1C; Differentiation antigen CD1 alpha 3 antibody R7; T cell surface glycoprotein CD1c; T-cell surface glycoprotein CD1c.
    产品应用WB=1:500-1000, IHC-P=1:50-200, IHC-F=1:50-200, IF=1:50-200

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Human
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human CD1c
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Recombinant
    理论分子量36 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Immunology > Adaptive Immunity > T Cells > CD

    Immunology > Immunoglobulins > Receptors

    亚细胞定位Nucleus.
    组织特异性Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
    相似性Contains 1 Ig-like (immunoglobulin-like) domain.
    功能 Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

     

    应用推荐稀释比例
    {WB}{1:500-1000}
    {IHC-P}{1:50-200}
    {IHC-F}{1:50-200}
    {IF}{1:50-200}

     

    CD1c Recombinant Rabbit mAb(bs
    Blocking buffer: 5% NFDM/TBST
    Primary Ab dilution: 1:2000
    Primary Ab incubation condition: 2 hours at
    room temperature
    Secondary Ab: Goat Anti-Rabbit IgG H&L
    (HRP)
    Lysate: 1: THP-1 (Negative control), 2:
    MOLT-4, 3: Jurkat
    Protein loading quantity: 20 μg
    Exposure time: 60 s
    Predicted MW: 38 kDa
    Observed MW: 43 kDa
    CD1c Recombinant Rabbit mAb(bs
    Tissue: Human spleen
    Section type: Formalin-fixed &
    Paraffin-embedded section
    Retrieval method: High temperature and high
    pressure
    Retrieval buffer: Tris/EDTA buffer, pH 9.0
    Primary Ab dilution: 1:100
    Primary Ab incubation condition: 1 hour at
    room temperature
    Secondary Ab: Anti-Rabbit and Mouse
    Polymer HRP (Ready to use)
    Counter stain: Hematoxylin (Blue)
    Comment: Color brown is the positive signal for
    bsm-60660R
    CD1c Recombinant Rabbit mAb(bs
    Tissue: Human tonsil
    Section type: Formalin-fixed &
    Paraffin-embedded section
    Retrieval method: High temperature and high
    pressure
    Retrieval buffer: Tris/EDTA buffer, pH 9.0
    Primary Ab dilution: 1:100
    Primary Ab incubation condition: 1 hour at
    room temperature
    Secondary Ab: Anti-Rabbit and Mouse
    Polymer HRP (Ready to use)
    Counter stain: Hematoxylin (Blue)
    Comment: Color brown is the positive signal for
    bsm-60660R

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