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- bsm-30025M
- 2026年10月14日
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100ug/200ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 200ug | 产品价格： | ￥5600.0 |
| 产品编号 | bsm-30025M |
| 英文名称 | human CD25 Mouse mAb |
| 中文名称 | 小鼠抗人CD25单克隆抗体 |
| 英文别名 | Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; IL2RA_HUMAN. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD25 |
| 亚型 | Mouse IgG2a, k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 28 kDa |
| 实际分子量 | 55kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4). |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > CD Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚基 | Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Contains 2 Sushi (CCP/SCR) domains. |
| 功能 | Receptor for interleukin-2. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
scatter diagram showing human peripheral blood lymphocytes stained with bsm-30025M. The cells were incubated with the antibody (bsm-30025M, 1ug/Test) for 30 min at room temperature.The secondary antibody used for 40 min at room temperature. Acquisition of >10,000 events was performed.
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文献和实验相关实验
The OP9-DL1 System: Generation of T-Lymphocytes from Embryonic or Hematopoietic Stem Cells In Vitro
. 36. Resuspend the cells in OP9 medium, seed 5 x 105 cells per 10-cm dish containing ~80% confluent OP9 cells in 10 mL of OP9 medium, and add 5 ng/mL of recombinant human Flt-3L. Return the dish to the incubator. The number of 10-cm dishes
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IL2RA | Human CD25/Tac Mouse mAb(bsm-30025M)-100ug/200ug
￥1880 - 5600
