- ￥1880 - 5600
- Bioss
- bsm-30025M
- 2025年10月24日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
PTPN12 Rabbit pAb, Biotin conjugated(bs-19589R-Bio)-100ul
￥2980phospho-Cardiac Troponin I (Ser23 + Ser24) Rabbit pAb, PE conjugated(bs-3458R-PE)-100ul
￥2980
MPO Rabbit pAb(bs-1061R)-50ul/100ul/200ul
￥1180
IL17D Rabbit pAb(bs-2612R)-50ul/100ul/200ul
￥1180IRF1 Rabbit pAb, Cy3 conjugated(bs-1404R-Cy3)-100ul
￥2980
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
100ug/200ug
| 规格： | 100ug | 产品价格： | ￥1880.0 |
|---|---|---|---|
| 规格： | 200ug | 产品价格： | ￥5600.0 |
| 产品编号 | bsm-30025M |
| 英文名称 | human CD25 Mouse mAb |
| 中文名称 | 小鼠抗人CD25单克隆抗体 |
| 英文别名 | Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; IL2RA_HUMAN. |
| 产品应用 | Flow-Cyt=1ug/Test Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Mouse |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD25 |
| 亚型 | Mouse IgG2a, k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 28 kDa |
| 实际分子量 | 55kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4). |
| 研究领域 | Immunology > Adaptive Immunity > T Cells > CD Immunology > Innate Immunity > Cytokines > Interleukins |
| 亚基 | Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Contains 2 Sushi (CCP/SCR) domains. |
| 功能 | Receptor for interleukin-2. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020] |
| 应用 | 推荐稀释比例 |
| {Flow-Cyt} | {1ug/Test} |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Antigen-Specific Human Monoclonal Antibodies from Transgenic Mice
of transgenic mice carrying immunoglobulin (Ig) genes in germ line configuration. The engineered mouse genome can undergo productive rearrangement in the B cell population, with the generation of mouse B lymphocytes expressing human Ig (hIg) chains. To avoid
Flow Cytometric Detection of Human Regulatory T Cells
if we are to understand their role in these increasingly common diseases. We have outlined below a flow cytometric technique to detect and isolate the entire human Treg population based on expression of CD4, CD25, and CD127. Use of a number of additional antibodies
Dual- and Triple-Color Fluorospot
antibodies (mAbs) to cytokines: Mouse mAb to human IFN-γ; mAb 1-D1K for coating and FITC-labeled mAb 7-B6-1 for detection. Mouse mAb to human IL-2; mAbs IL2-I/249 for coating and biotinylated mAb IL2-II for detection. If a third cytokine is included
技术资料暂无技术资料 索取技术资料
