Sample:
Lane 1: U251 cell lysates
Primary: Anti-RYK (bsm-51489M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 68 kD
- ￥1180 - 1980
- Bioss
- bsm-51489M
- 2025年10月24日
- 产品信息以Bioss网站为准
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- 规格：
50ul/100ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 产品编号 | bsm-51489M |
| 英文名称 | RYK Mouse mAb |
| 中文名称 | RYK单克隆抗体 |
| 英文别名 | D3S3195; ERK 3; Hydroxyaryl protein kinase; JTK 5; JTK 5A; JTK5; JTK5A; JTK5A protein tyrosine kinase; receptor like tyrosine kinase; receptor like tyrosine kinase precursor; RYK 1; RYK_HUMAN; RYK1; Tyrosine protein kinase RYK; Tyrosine protein kinase RYK precursor; Tyrosine-protein kinase RYK; Vik; |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Human |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human RYK. |
| 亚型 | IgG2b,k |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein G |
| 克隆类型 | Monoclonal |
| 理论分子量 | 68 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Signal Transduction > Protein Phosphorylation > Tyrosine Kinases > Receptor Tyrosine Kinases Stem Cells > Signaling Pathways > Wnt > Surface Molecules |
| 组织特异性 | Observed in all the tissues examined. |
| 相似性 | Belongs to the protein kinase superfamily. Tyr protein kinase family. Contains 1 protein kinase domain. Contains 1 WIF domain. |
| 功能 | May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012] |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
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RYK Mouse mAb(bsm-51489M)-50ul/100ul
￥1180 - 1980
