Sample:
Lane 1: Ovary (Rat) Lysate at 40 ug
Lane 2: Testis (Rat) Lysate at 40 ug
Primary: Anti-TIMP-2 (bs-21340R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 22 kD
- ￥1180 - 2800
- Bioss
- bs-21340R
- 2025年10月16日
- 产品信息以Bioss网站为准
企业认证
相关产品推荐更多 >
Pancreatic hormone Rabbit pAb, AP conjugated(bs-8543R-AP)-100ul
￥2980
TPSB2 Rabbit pAb, HRP conjugated(bs-20844R-HRP)-100ul
￥2980SOD1 Rabbit pAb, BF405 conjugated(bs-10216R-BF405)-100ul
￥2980
phospho-NFAT2 (Ser233) Rabbit pAb(bs-19785R)-50ul/100ul/200ul
￥1180CD68 Rabbit pAb(bs-42013R)-50ul/100ul/200ul
￥1180
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 应用范围：
产品信息以Bioss网站为准
- 规格：
50ul/100ul/200ul
| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-21340R |
| 英文名称 | TIMP-2 Rabbit pAb |
| 中文名称 | 金属蛋白酶组织抑制因子-2抗体 |
| 英文别名 | Metalloproteinase inhibitor 2 precursor; Tissue inhibitor of metalloproteinases 2; Collagenase inhibitor; CSC 21K; CSC21K; TIMP2; TIMP 2; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP2_HUMAN; Metalloproteinase inhibitor 2; CSC-21K; TIMP-2. |
| 产品应用 | WB=1:500-2000 Not yet tested in other applications. |
| 交叉反应 | Mouse, Rat (Human, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human TIMP-2 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 24 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Invasion/microenvironment > Angiogenesis > ECM enzymes > TIMPs Cancer > Invasion/microenvironment > ECM > Extracellular matrix > TIMPs Cardiovascular > Angiogenesis > Adhesion / ECM > Matrix Metalloproteinases > TIMP Cardiovascular > Atherosclerosis > Thrombosis > Endothelial mediators/regulators Cell Biology > Proteolysis / Ubiquitin > Protease inhibitors > Metalloprotease inhibitors > TIMPs Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Enzymes > MMP Inhibitors |
| 亚基 | Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity. |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | The activity of TIMP2 is dependent on the presence of disulfide bonds. |
| 相似性 | Belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain. |
| 功能 | Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-13, MMP-14, MMP-15, MMP-16 and MMP-19. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq, Jul 2008]. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
Sample:
Lane 1: Testis (Mouse) Lysate at 40 ug
Lane 2: Hippocampus (Mouse) Lysate at 40 ug
Primary: Anti-TIMP-2 (bs-21340R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 20 kD
Lane 1: Testis (Mouse) Lysate at 40 ug
Lane 2: Hippocampus (Mouse) Lysate at 40 ug
Primary: Anti-TIMP-2 (bs-21340R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 22 kD
Observed band size: 20 kD
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验相关实验
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
分子 -1 (rabbit ICAM-1) ELISA 48T/96T 2000/3000 进口分装 F20170 兔干扰素 -r(rabbit IFN-r) ELISA 48T/96T 1500/2500 进口分装 F20180 兔白介素
/3000 进口分装 F1162 小鼠基质金属蛋白酶抑制剂-2(mouse TIMP-2) ELISA 48T/96T 2000/3000 进口分装 F1163 ★ 小鼠肿瘤坏死因子- a (mouse TNF- a ) ELISA 48T/96T 1300/2300 进口分装 F1164 小鼠可溶性肿瘤坏死因子- 受体 (mouse sTNF-R) ELISA 48T/96T 1300/2300 进口分装 F1165 小鼠
技术资料暂无技术资料 索取技术资料
TIMP-2 Rabbit pAb(bs-21340R)-50ul/100ul/200ul
￥1180 - 2800
