BMS-986251 is an orally active and selective RORγt inverse agonist with an EC50 of 12 nM for RORγt GAL4. BMS-986251 inhibits IL-17 with an EC50 of 24 nM in human whole blood assay. BMS-986251 demonstrates robust efficacy in mouse acanthosis and Imiquimod-induced models (preclinical models of psoriasis).
产品名:BMS-986251
货号:orb1910826
产品中文名:BMS-986251
产品详情链接:https://www.biorbyt.com/bms-986251-orb1910826.html