- ￥2106 - 8658
- Biorbyt
- 英国
- orb1819238
- 2026年08月07日
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- 文献和实验
- 技术资料
- 保存条件：
详询
- 保质期：
12 months from date of receipt.
- 英文名：
FA16
- 库存：
99
- 供应商：
Biorbyt
- 规格：
1 mg/5 mg/10 mg/25 mg
| 规格： | 1 mg | 产品价格： | ￥2106.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥4095.0 |
| 规格： | 10 mg | 产品价格： | ￥5733.0 |
| 规格： | 25 mg | 产品价格： | ￥8658.0 |
类别: Small Molecules
描述: FA16 is a selective and metabolically stable 2-(trifluoromethyl)benzimidazole derivative that potently induces ferroptosis by inhibiting system Xc- (IC50 = 1.26 μM). It blocks cystine/glutamate exchange, leading to glutathione depletion and lipid peroxidation. This compound has demonstrated significant antitumor efficacy in a HepG2 xenograft model, supporting its use in researching ferroptosis-dependent cancer therapies.
别名: FA-16, FA16, FA 16, Ferroptosis
靶点: Ferroptosis
分子式: C22H27F3N4O2S
分子量: 468.54
纯度: 99.44% (May vary between batches)
SMILES: FC(F)(F)C(N=C1C2C=CC=C1)N2CC(CC3)CCN3C4=CC=C(S(N(C)C)(=O)=O)C=C4
溶解度: DMSO:4.69 mg/mL (10.01 mM)
研究领域: Cell Biology
保存条件: -20°C
备注: For research use only.
描述: FA16 is a selective and metabolically stable 2-(trifluoromethyl)benzimidazole derivative that potently induces ferroptosis by inhibiting system Xc- (IC50 = 1.26 μM). It blocks cystine/glutamate exchange, leading to glutathione depletion and lipid peroxidation. This compound has demonstrated significant antitumor efficacy in a HepG2 xenograft model, supporting its use in researching ferroptosis-dependent cancer therapies.
别名: FA-16, FA16, FA 16, Ferroptosis
靶点: Ferroptosis
分子式: C22H27F3N4O2S
分子量: 468.54
纯度: 99.44% (May vary between batches)
SMILES: FC(F)(F)C(N=C1C2C=CC=C1)N2CC(CC3)CCN3C4=CC=C(S(N(C)C)(=O)=O)C=C4
溶解度: DMSO:4.69 mg/mL (10.01 mM)
研究领域: Cell Biology
保存条件: -20°C
备注: For research use only.
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FA16，orb1819238，Biorbyt
￥2106 - 8658
