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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).
- 保质期:
6个月
- 英文名:
Human p16(110-139) Protein, hFc Tag
- 库存:
详询客服
- 供应商:
biorbyt
- 规格:
10 ug
产品别名:CDKN2A;ARF;MLM;P14;P19;CMM2;INK4;MTS1;TP16;CDK4I;CDKN2;INK4A;MTS-1;P14ARF;P19ARF;P16INK4;P16INK4A;P16-INK4A
反应种属:Human
纯度:The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
分子量:The protein has a predicted molecular mass of 29.4 kDa after removal of the signal peptide. The apparent molecular mass of hFc-p16(110-139) is approximately 25-35 kDa due to glycosylation.
标签:N-Human Fc Tag
来源:Mammalian
形态:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Uniprot ID:P42771
Note:For research use only.

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文献和实验Abrogation of the RB-p16Tumor Suppressor Pathway in Human Lung Cancer
There is compelling evidence that human lung cancers are characterized by disruption of several important physiological pathways that govern proliferation, apoptosis, intracellular signaling, and cell-cell interactions. Uncontrolled cellular
p16INK4A and Familial Melanoma
. This phase is controlled by several protein complexes including those consisting of cyclin-dependent kinases (CDK4 and CDK6) and cyclin D. These complexes are inhibited by the INK4 family of proteins—p16INK4A , p15INK4B , p18INK4C , and p19INK4D . Genetic
Prediction of Protein‐Protein Interaction Networks
., Ghosh, D., Pandey, A., and Chinnaiyan, A.M. 2005. Probabilistic model of the human protein‐protein interaction network. Nat. Biotechnol. 23:951‐959. Riley, R., Lee, C
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