- ￥3770
- biorbyt
- 7.81-500pg/mL
- 4.69 pg/mL
- orb1806816
- 英国
- 2026年01月21日
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- 详细信息
- 文献和实验
- 技术资料
- 库存：
999
- 供应商：
biorbyt
- 检测范围：
7.81-500pg/mL
- 检测方法：
Competitive
- 适应物种：
Rat
- 样本：
serum, plasma, Tissue homogenate and Other biological samples
- 灵敏度：
4.69 pg/mL
- 规格：
48 T
产品别名：Thyrotropin-releasing hormone, TRH, Protirelin, TSH-releasing factor, Thyroliberin, Thyrotropin-releasing factor, TRF
应用笔记：This ELISA kit uses the Competitive-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with Rat TRH. During the reaction, Rat TRH in the sample or standard competes with a fixed amount of Rat TRH on the solid phase supporter for sites on the Biotinylated Detection Ab specific to Rat TRH. Excess conjugate and unbound sample or standard are washed away, and Avidin-Horseradish Peroxidase (HRP) conjugate are added to each micro plate well and incubated. Then a TMB substrate solution is added to each well. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns from blue to yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm ± 2 nm. The concentration of Rat TRH in tested samples can be calculated by comparing the OD of the samples to the standard curve.
实验时长：1.5H
UniProt ID:P01150
靶点：TRH
Note：For research use only.
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文献和实验促甲状腺激素释放激素（thyrotropin-releasing hormone，TRH）
为下丘脑中促垂体激素的一种。其成分为肽类。等克分子量的谷氨酸，组氨酸及脯氨酸结合成三肽，即：焦性谷氨酸—组氨酸—脯氨酰胺。分子量为362。TRH广泛分布于下丘脑以外的脑脊髓部分。为内源性中枢刺激物。如低等脊椎动物无垂体但体内TRH含量多，表明其原始作用为调节神经系统功能。可能作为递质存在。由下丘脑分泌的TRH经垂体门脉运至腺垂体，作用于腺垂体的促甲状腺细胞，与细胞膜上受体结合，激活腺苷酸环化酶-cAMP-蛋白激酶系统，使促甲状腺细胞合成与释放促甲状腺激素，并维持其正常分泌
Null Mutant Mice for Thyroid Hormone Receptors
of two peptidic hormones, thyrotropin-releasing hormone (TRH) in the hypothalamus and thyroid-stimulating hormone (TSH) in the pituitary. TRH normally stimulates the production of TSH, which, in turn, stimulates the thyroid gland and thus permits an efficient TH
Prodrug Design for Brain Delivery of Small- and Medium-Sized Neuropeptides
for brain delivery of small neuropeptides, pGlu-Glu-Pro-NH2 , [Glu2 TRH], a thyrotropin-releasing hormone (TRH) analogue with a vast array of central activities, was chosen as an example. An ester prodrug provided significantly improved brain
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