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- 文献和实验
- 技术资料
- 抗体名:
GRP78 (Bip) Antibody 抗体
- 抗体英文名:
GRP78 (Bip) Antibody
- 靶点:
GRP78 (Bip)
- 浓度:
1 mg/ml
- 应用范围:
ELISA, ICC, IF, IHC, WB
- 宿主:
Rabbit
- 适应物种:
Canine, Drosophila, Hamster, Human, Mouse, Rat
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb1822422
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
Polyclonal
- 保存条件:
详询
- 免疫原:
详询
- 规格:
100 ug
描述: Rabbit Anti-Human GRP78 (Bip) Polyclonal
别名: GRP78, GRP-78, Grp78, GRP 78, HSPA5, HSPA 5, Heat shock 70 kDa protein 5, Heat Shock 70kDa Protein 5, BiP, BIP, Binding immunoglobulin protein, Immunoglobulin heavy chain-binding protein, Immunoglobulin Heavy Chain Binding Protein, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Endoplasmic reticulum lumenal, Ca2+ binding protein grp78, Glucose Regulated Protein 78kDa, 78 kDa glucose-regulated protein, 78 kDa glucose regulated protein, HSCe70, MIF2, mBiP, Sez7, AL022860, AU019543, D2Wsu141e, D2Wsu17e, FLJ26106, GRP78_HUMAN
应用稀释比例: WB (1:2000), ICC/IF (1:100); optimal dilutions for assays should be determined by the user.
应用说明: 0.5 µg/ml was sufficient for detection of Grp78 in 10 µg of rat tissue lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
免疫原: Full length human GRP78 (Bip) his tagged at the N terminus
分子量: 78kDa
防腐剂: PBS, 50% glycerol, 0.09% sodium azide. Storage buffer changes when conjugated.
纯化方法: Protein A Purified
特异性: Detects ~78kDa.
研究领域: Cell Biology
UniProt ID: P11021
NCBI 参考序列: NP_005338.1
Entrez 基因 ID: 3309
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.


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文献和实验with chaperones in these cells is of interest. Furthermore, Pb and Cu bind strongly to the molecular chaperone heat shock 70 kDa protein Hspa5, also known as glucose-regulated protein 78 (Grp78) or immunoglobulin-binding protein (BiP). This chapter describes
网膜上也存在Bak等凋亡蛋白,在凋亡因子的刺激下,Bax也能在内质网上富聚,Bax和Bak的多聚化和caspase·12的激活可导致细胞凋亡(Zong et al.2003)。 内质网是细胞内蛋白质合成 和成熟的主要场所,蛋白质成熟和折叠的异常可导致内质网损伤。如用衣霉素(tunicamycin)抑制蛋白质糖基化或改变内质网内的氧化还原状态使蛋白质糖基化和蛋白质二硫键形成发生异常,可使没有折叠奸的蛋白质在内质网内积累。未折叠的蛋白质与内质网内伴侣蛋白BiP/Grp78结合,从而BiP/Grp78
=0 [求助]有抗人的GRP78的抗体吗?最好是兔抗 用于做IP http://www.dxy.cn/bbs/post/view?bid=65&id=5314820&sty=1&tpg=39&age=0 [求助]急问各位大侠过滤参数的问题 http://www.dxy.cn/bbs/post/view?bid=65&id=5314816&sty=1&tpg=39&age=0 [求助]内参 http://www.dxy.cn/bbs/post/view?bid=65&id=5314250
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