- ￥9932
- Biorbyt
- orb1826174
- 英国
- 2025年07月09日
- IHC-P
- Rabbit
- Human
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- 详细信息
- 技术资料
- 抗体名：
MGMT Antibody 抗体
- 抗体英文名：
MGMT Antibody
- 浓度：
详询
- 应用范围：
IHC-P
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1826174
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Aliquot the MGMT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态：
详询
- 亚型：
Rabbit IgG, kappa
- 免疫原：
A recombinant partial protein (within amino acids 1-100) from the human protein was used as the immunogen for the MGMT antibody.
- 规格：
100 ug
Cancer chemotherapeutic alkylating agents (e.g. BCNU,) act by inducing formation of lethal cross-links at the O6- alkylguanine position in DNA. MGMT transfers alkyl adducts from the O6- position of guanine in DNA (prior to cross-link formation) to a cysteine residue in its own sequence, thereby restoring DNA to its intact state. This transfer inactivates the MGMT enzyme and is irreversible; hence the level of MGMT in a cell is directly proportional to the level of DNA damage it can tolerate. In normal tissues, MGMT acts as a suppressor of mutation and carcinogenesis. Tumors with high levels of MGMT are likely to be drug resistant.
产品名：MGMT Antibody
货号：orb1826174
产品中文名：MGMT Antibody 抗体
产品详情链接：https://www.biorbyt.com/mgmt-antibody-orb1826174.html
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MGMT Antibody 抗体，orb1826174，Biorbyt
￥9932
