- ￥5265
- Biorbyt
- orb1826124
- 英国
- 2025年07月16日
- IHC-P
- Mouse
- Human
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- 详细信息
- 技术资料
- 抗体名：
Tryptophan Hydroxylase Antibody / TPH1 抗体
- 抗体英文名：
Tryptophan Hydroxylase Antibody / TPH1
- 浓度：
详询
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1826124
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Aliquot the Tryptophan Hydroxylase 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态：
详询
- 亚型：
Mouse IgG2, kappa
- 免疫原：
Recombinant full-length human TPH1 protein was used as the immunogen for the Tryptophan Hydroxylase 1 antibody.
- 规格：
20 ug
Phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and tryptophan hydroxylase (TPH) comprise a small family of monooxygenases that use tetrahydropterine as a cofactor during the catabolism of aromatic L-amino acids. PAH, TH and TPH all contain catalytic domains with an amino-terminal regulatory domain and a short carboxy-terminal tetramerization domain. Each of these enzymes also contains a single ferrous iron atom, which is bound to two histidines and a glutamate, and is likely to be involved in the formation of the hydroxylating intermediate. TPH is both the first and rate-limiting-step in the biosynthesis of serotonin in the central nervous system and melatonin in the pineal gland. Alteration of TPH function may be a key factor in the pathology of several neuropsychiatric disorders associated with serotonin, including depression, aggression, alcoholism and schizophrenia. For instance, LDOPA, which is used as a common therapy for Parkinson s disease (PD) patients, inhibits TPH function which, subsequently, is thought to contribute to the onset of depression in PD patients.
产品名：Tryptophan Hydroxylase Antibody / TPH1
货号：orb1826124
产品中文名：Tryptophan Hydroxylase Antibody / TPH1 抗体
产品详情链接：https://www.biorbyt.com/tryptophan-hydroxylase-antibod-orb1826124.html
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Tryptophan Hydroxylase Antibody / TPH1 抗体，orb1826124，Biorbyt
￥5265
