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- 详细信息
- 技术资料
- 抗体名:
FLI1 Antibody 抗体
- 抗体英文名:
FLI1 Antibody
- 浓度:
详询
- 应用范围:
IHC-P, WB
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1825928
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
MONOCLONAL
- 保存条件:
Aliquot the FLI1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态:
详询
- 亚型:
Mouse IgG2, kappa
- 免疫原:
A recombinant partial protein (within amino acids 107-261) from the human protein was used as the immunogen for the FLI1 antibody.
- 规格:
100 ug
Recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewing s Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11;22)(q24;q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
产品名:FLI1 Antibody
货号:orb1825928
产品中文名:FLI1 Antibody 抗体
产品详情链接:https://www.biorbyt.com/fli1-antibody-orb1825928.html
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FLI1 Antibody 抗体,orb1825928,Biorbyt
¥9932










