FLI1 Antibody 抗体,orb1825928,Biorbyt

FLI1 Antibody 抗体,orb1825928,Bi

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  • ¥9932
  • Biorbyt已认证
  • orb1825928
  • 英国
  • 2025年07月14日
  • IHC-P, WB
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 抗体名

      FLI1 Antibody 抗体

    • 抗体英文名

      FLI1 Antibody

    • 浓度

      详询

    • 应用范围

      IHC-P, WB

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb1825928

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      MONOCLONAL

    • 保存条件

      Aliquot the FLI1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

    • 形态

      详询

    • 亚型

      Mouse IgG2, kappa

    • 免疫原

      A recombinant partial protein (within amino acids 107-261) from the human protein was used as the immunogen for the FLI1 antibody.

    • 规格

      100 ug

    FLI1 Antibody 抗体,orb1825928,Bi
     

    Recognizes a protein of 51kDa, which is identified as FLI1. This protein, a member of the ETS family of DNA binding transcription factors, is involved in cellular proliferation and tumorigenesis. Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. Members of the Ets gene family share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. Approximately 90% of Ewing s Sarcoma (EWS) / Primitive Neuroectodermal Tumors (PNET) have a specific translocation, t(11;22)(q24;q12), which results in fusion of EWS to Fli-1, and production of an EWS-Fli-1 fusion protein. Among normal tissues only endothelial cells and small lymphocytes express Fli-1. This protein is expressed in majority of vascular tumors including angiosarcomas, hemangioendotheliomas, hemangiomas, and Kaposi s Sarcomas. High sensitivity and specificity of Fli-1 equals to or exceeds that of the established vascular markers like CD31, CD34, and Factor VIII.
    产品名:FLI1 Antibody
    货号:orb1825928
    产品中文名:FLI1 Antibody 抗体
    产品详情链接:https://www.biorbyt.com/fli1-antibody-orb1825928.html

    FLI1 Antibody 抗体,orb1825928,Bi
     

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