Aliquot the Estrogen Inducible Protein pS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
形态:
详询
亚型:
Mouse IgG
免疫原:
A recombinant partial protein sequence (within amino acids 1-84) from the human protein was used as the immunogen for the Estrogen Inducible Protein pS2 antibody.
规格:
100 ug
It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
产品名:Estrogen Inducible Protein pS2 / TFF1 Antibody
货号:orb1825387
产品中文名:Estrogen Inducible Protein pS2 / TFF1 Antibody 抗体
产品详情链接:https://www.biorbyt.com/estrogen-inducible-protein-ps2-orb1825387.html