Estrogen Inducible Protein pS2 / TFF1 Antibody 抗体,orb1825383,Biorbyt

Estrogen Inducible Protein pS2

/ TFF1 Antibody 抗体,orb1825383,Biorbyt
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  • ¥5265
  • Biorbyt已认证
  • orb1825383
  • 英国
  • 2025年07月13日
  • IHC-P
  • Mouse
  • Human
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    • 详细信息
    • 技术资料
    • 抗体名

      Estrogen Inducible Protein pS2 / TFF1 Antibody 抗体

    • 抗体英文名

      Estrogen Inducible Protein pS2 / TFF1 Antibody

    • 浓度

      详询

    • 应用范围

      IHC-P

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb1825383

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      MONOCLONAL

    • 保存条件

      Aliquot the Estrogen Inducible Protein pS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

    • 形态

      详询

    • 亚型

      Mouse IgG1, kappa

    • 免疫原

      A recombinant partial protein sequence (within amino acids 1-84) from the human protein was used as the immunogen for the Estrogen Inducible Protein pS2 antibody.

    • 规格

      20 ug

    Estrogen Inducible Protein pS2
     

    It recognizes a polypeptide of 6.5kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.
    产品名:Estrogen Inducible Protein pS2 / TFF1 Antibody
    货号:orb1825383
    产品中文名:Estrogen Inducible Protein pS2 / TFF1 Antibody 抗体
    产品详情链接:https://www.biorbyt.com/estrogen-inducible-protein-ps2-orb1825383.html

    Estrogen Inducible Protein pS2
     

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