- ￥5265
- Biorbyt
- orb1825422
- 英国
- 2025年07月16日
- IHC-P
- Mouse
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 抗体名：
TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin 抗体
- 抗体英文名：
TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin
- 浓度：
详询
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1825422
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Aliquot the Alpha Tropomyosin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态：
详询
- 亚型：
Mouse IgG1
- 免疫原：
Recombinant full-length protein was used as the immunogen for the Alpha Tropomyosin antibody.
- 规格：
20 ug
Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind actin filaments and function to modulate Actin-myosin interaction and stabilize actin filament structure. Tropomyosin Alpha is encoded by the TPM1 gene, which maps to human chromosome 15q22.2 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Tropomyosin b is encoded by the TPM2 gene, which maps to human chromosome 9p13.3 and undergoes alternative splicing to generate three isoforms, including skeletal muscle (isoform 1), non-muscle/fibroblast TM36/epithelial TMe1 (isoform 2) and non-muscle (isoform 3). Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with actin filaments may increase the rigidity of actin filaments. Tropomyosin also interacts with caldesmon to regulate smooth muscle contraction.
产品名：TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin
货号：orb1825422
产品中文名：TPM1 Antibody / Tropomyosin-1 / Alpha Tropomyosin 抗体
产品详情链接：https://www.biorbyt.com/tpm1-antibody-tropomyosin-1-orb1825422.html
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文献和实验Protein purification: tropomyosin
Overview TROPOMYOSIN An ubiquitous actin binding protein arranged in alpha-helical coiled-coil of 410 Angstrom length
In situ hybridisation to alpha satellite sequences (chromosome specific)
Alpha satellite sequences, whilst highly repetitive, are specific to each individual chromosome. These sequences flank the centromeres and can present a target measured in megabases. In this protocol a biotin or digoxigenin labelled DNA
troponin蛋白纯化 Protein purification: troponins
); centrifuge at 10.9 x g for 10 min 3. (take pellet) reextract, add 1 M KCl to centrifuge bottles (7.5:1, v/w); centrifuge at 10.9 x g for 10 min 4. (take supernatant) lower pH to 4.6 by adding 1 N HCl, remove precipitate (tropomyosin
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