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- 详细信息
- 技术资料
- 抗体名:
ICOS-L Antibody / ICOS Ligand / B7RP-1 抗体
- 抗体英文名:
ICOS-L Antibody / ICOS Ligand / B7RP-1
- 浓度:
详询
- 应用范围:
IHC-P
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1824074
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
MONOCLONAL
- 保存条件:
Aliquot the B7RP-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态:
详询
- 亚型:
Mouse IgG2b, kappa
- 免疫原:
A recombinant fragment of human ICOSLG/B7RP-1 protein (within amino acids 1-300) was used as the immunogen for the B7RP-1 antibody.
- 规格:
100 ug
This mAb recognizes a protein of 36kDa, identified as ICOS-L, also called B7RP-1 or B7-related protein 1. It is a ligand for the ICOS receptor that initiates T and B cell proliferation and cytokine secretion. ICOS-L interactions play an essential role in T cell-dependent B cell activation in peripheral lymphoid organs such as spleen and lymph nodes. ICOS-L protein is present in myeloid leukocytes, and by Northern blot there are 2.4, 3.0, and 7.0 kb transcripts in brain, heart, kidney, and liver, with lower expression in colon and thymus, and a 1.1 kb transcript in leukocytes. Tumor necrosis factor alpha (TNF Alpha), granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-4 (IL-4) enhance its expression. LPS-induced up-regulation of ICOS-L is dependent on the MyD88-dependent signaling pathway.
产品名:ICOS-L Antibody / ICOS Ligand / B7RP-1
货号:orb1824074
产品中文名:ICOS-L Antibody / ICOS Ligand / B7RP-1 抗体
产品详情链接:https://www.biorbyt.com/icos-l-antibody-icos-ligand-orb1824074.html
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ICOS-L Antibody / ICOS Ligand / B7RP-1 抗体,orb1824074,Biorbyt
¥9932










