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- 详细信息
- 技术资料
- 抗体名:
GBX2 Antibody / Gastrulation Brain Homeobox 2 抗体
- 抗体英文名:
GBX2 Antibody / Gastrulation Brain Homeobox 2
- 浓度:
详询
- 应用范围:
IHC-P
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1823711
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
MONOCLONAL
- 保存条件:
Aliquot the GBX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态:
详询
- 亚型:
Mouse IgG2, kappa
- 免疫原:
A recombinant partial protein sequence (within amino acids 150-350) from the human protein was used as the immunogen for the GBX2 antibody.
- 规格:
100 ug
The isthmic organizer signals at the mid/hindbrain boundary (MHB) regulate the development and differentiation of the vertebrate caudal midbrain and the anterior hindbrain. The MHB forms at the boundary of expression between homeobox genes GBX2 and OTX2. GBX2 and OTX2 play distinct, essential roles in MHB positioning and development. During development, the GBX2 gene is expressed in the anterior hindbrain. Specifically, GBX2 negatively regulates OTX2 expression along the anterior-posterior axis; GBX2- mutants demonstrate an expanded OTX2 domain. During development, the GBX2 gene is expressed in the anterior hindbrain. GBX2 is expressed in the adult brain, spleen and female genital tract. The GBX2 gene is overexpressed in human prostate cancer cell lines (TSU-prl, PC3, DU145 and LNCaP). Furthermore, downregulation of GBX2 expression restricts tumorigenicity in human prostate cancer cell lines, which suggests that GBX2 expression may be required for growth of malignant prostate cells.
产品名:GBX2 Antibody / Gastrulation Brain Homeobox 2
货号:orb1823711
产品中文名:GBX2 Antibody / Gastrulation Brain Homeobox 2 抗体
产品详情链接:https://www.biorbyt.com/gbx2-antibody-gastrulation-b-orb1823711.html
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GBX2 Antibody / Gastrulation Brain Homeobox 2 抗体,orb1823711,Biorbyt
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