- ￥5265
- Biorbyt
- orb1823013
- 英国
- 2025年07月16日
- IHC-P
- Mouse
- Human
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- 详细信息
- 技术资料
- 抗体名：
Fascin 1 Antibody 抗体
- 抗体英文名：
Fascin 1 Antibody
- 浓度：
详询
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1823013
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Aliquot the Fascin 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态：
详询
- 亚型：
Mouse IgG2a, kappa
- 免疫原：
A recombinant partial protein sequence (within amino acids 350-400) from the human protein was used as the immunogen for the Fascin 1 antibody.
- 规格：
20 ug
Recognizes a protein of 55kDa, which is identified as fascin-1. Its actin binding ability is regulated by phosphorylation. Antibody to fascin-1 is a very sensitive marker for Reed-Sternberg cells and variants in nodular sclerosis, mixed cellularity, and lymphocyte depletion Hodgkin s disease. It is uniformly negative in lymphoid cells, plasma cells, and myeloid cells. Fascin-1 is also expressed in dendritic cells. This marker may be helpful to distinguish between Hodgkin lymphoma and non-Hodgkin lymphoma in difficult cases. Also, the lack of expression of fascin-1 in the neoplastic follicles in follicular lymphoma may be helpful in distinguishing these lymphomas from reactive follicular hyperplasia in which the number of follicular dendritic cells is normal or increased. Antibody to fascin-1 has been suggested as a prognostic marker in neuroendocrine neoplasms of the lung as well as in ovarian cancer. Fascin-1 expression may be induced by Epstein-Barr virus (EBV) infection of B cells with the possibility that viral induction of fascin in lymphoid or other cell types must also be considered in EBV-positive cases.
产品名：Fascin 1 Antibody
货号：orb1823013
产品中文名：Fascin 1 Antibody 抗体
产品详情链接：https://www.biorbyt.com/fascin-1-antibody-orb1823013.html
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Fascin 1 Antibody 抗体，orb1823013，Biorbyt
￥5265
