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- 详细信息
- 技术资料
- 抗体名:
KDM5C Antibody / JARID1C / SMCX 抗体
- 抗体英文名:
KDM5C Antibody / JARID1C / SMCX
- 浓度:
详询
- 应用范围:
FACS
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1822643
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
MONOCLONAL
- 保存条件:
Aliquot the JARID1C antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态:
详询
- 亚型:
Mouse IgG2c
- 免疫原:
Recombinant full-length human protein was used as the immunogen for the JARID1C antibody.
- 规格:
100 ug
SmcX, also known as JARID1C (jumonji, AT rich interactive domain 1C), MRXJ, KDM5C or XE169, is a nuclear protein that contains one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers and belongs to the JARID1 histone demethylase family. Expressed ubiquitously with highest expression in brain and skeletal muscle, SmcX functions as a histone demethylase that removes methyl groups from lysine residues on Histone H3, thereby playing a role in the histone code, as well as transcriptional regulation and chromatin remodeling. SmcX binds iron and a-ketoglutarate as cofactors and can recruit histone deacetylases to neuron silencer elements, thus repressing the transcription of neuronal genes. Defects in the gene encoding SmcX are associated with X-linked mental retardation (XLMR), a condition characterized by cognitive impairment and a low IQ. Multiple isoforms of SmcX are expressed due to alternative splicing events.
产品名:KDM5C Antibody / JARID1C / SMCX
货号:orb1822643
产品中文名:KDM5C Antibody / JARID1C / SMCX 抗体
产品详情链接:https://www.biorbyt.com/kdm5c-antibody-jarid1c-smc-orb1822643.html
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KDM5C Antibody / JARID1C / SMCX 抗体,orb1822643,Biorbyt
¥9932










