- ￥3795
- Biorbyt
- orb1732844
- 英国
- 2025年07月10日
- WB
- Mouse
- Human, Mouse
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- 详细信息
- 技术资料
- 抗体名：
Nucleophosmin Antibody 抗体
- 抗体英文名：
Nucleophosmin Antibody
- 浓度：
1mg/ml
- 应用范围：
WB
- 宿主：
Mouse
- 适应物种：
Human, Mouse
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1732844
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- 形态：
详询
- 亚型：
Mouse IgG1
- 免疫原：
Purified recombinant full length of human NPM1 protein expressed in E.coli.
- 规格：
100 ul
Involved in diverse cellular processes such as ribosome biogenesis, centrosome duplication, protein chaperoning, histone assembly, cell proliferation, and regulation of tumor suppressors p53/TP53 and ARF. Binds ribosome presumably to drive ribosome nuclear export. Associated with nucleolar ribonucleoprotein structures and bind single-stranded nucleic acids. Acts as a chaperonin for the core histones H3, H2B and H4. Stimulates APEX1 endonuclease activity on apurinic/apyrimidinic (AP) double-stranded DNA but inhibits APEX1 endonuclease activity on AP single-stranded RNA. May exert a control of APEX1 endonuclease activity within nucleoli devoted to repair AP on rDNA and the removal of oxidized rRNA molecules. In concert with BRCA2, regulates centrosome duplication. Regulates centriole duplication: phosphorylation by PLK2 is able to trigger centriole replication. Negatively regulates the activation of EIF2AK2/PKR and suppresses apoptosis through inhibition of EIF2AK2/PKR autophosphorylation. Antagonizes the inhibitory effect of ATF5 on cell proliferation and relieves ATF5-induced G2/M blockade (PubMed:22528486). In complex with MYC enhances the transcription of MYC target genes (PubMed:25956029).
产品名：Nucleophosmin Antibody
货号：orb1732844
产品中文名：Nucleophosmin Antibody 抗体
产品详情链接：https://www.biorbyt.com/nucleophosmin-antibody-orb1732844.html
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Nucleophosmin Antibody 抗体，orb1732844，Biorbyt
￥3795
