VPS4A Antibody 抗体,orb1731195,Biorbyt

VPS4A Antibody 抗体,orb1731195,B

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  • ¥3795
  • Biorbyt已认证
  • orb1731195
  • 英国
  • 2025年07月09日
  • ICC, IHC, WB
  • Rabbit
  • Human, Mouse, Rat
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    • 详细信息
    • 技术资料
    • 抗体名

      VPS4A Antibody 抗体

    • 抗体英文名

      VPS4A Antibody

    • 浓度

      1mg/ml

    • 应用范围

      ICC, IHC, WB

    • 宿主

      Rabbit

    • 适应物种

      Human, Mouse, Rat

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb1731195

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      MONOCLONAL

    • 保存条件

      Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

    • 形态

      详询

    • 亚型

      Rabbit IgG

    • 免疫原

      A synthetic peptide of human VPS4a

    • 规格

      100 ul

    VPS4A Antibody 抗体,orb1731195,B
     

    Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the cytoplasm for further rounds of MVB sorting. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. In conjunction with the ESCRT machinery also appears to function in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Involved in cytokinesis: retained at the midbody by ZFYVE19/ANCHR and CHMP4C until abscission checkpoint signaling is terminated at late cytokinesis. It is then released following dephosphorylation of CHMP4C, leading to abscission (PubMed:24814515). VPS4A/B are required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).
    产品名:VPS4A Antibody
    货号:orb1731195
    产品中文名:VPS4A Antibody 抗体
    产品详情链接:https://www.biorbyt.com/vps4a-antibody-orb1731195.html

    VPS4A Antibody 抗体,orb1731195,B
     

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