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Cytokeratin 14 Antibody / CK14

/ KRT14 抗体,orb1716212,Biorbyt
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  • ¥5265
  • Biorbyt已认证
  • orb1716212
  • 英国
  • 2025年07月11日
  • IHC-P, WB
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Cytokeratin 14 Antibody / CK14 / KRT14 抗体

    • 抗体英文名

      Cytokeratin 14 Antibody / CK14 / KRT14

    • 浓度

      详询

    • 应用范围

      IHC-P, WB

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb1716212

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      MONOCLONAL

    • 保存条件

      Aliquot the KRT14 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

    • 形态

      详询

    • 亚型

      Mouse IgG2b, kappa

    • 免疫原

      A portion of amino acids 350-472 was used as the immunogen for the KRT14 antibody.

    • 规格

      20 ug

    产品细节图片1
     

    Cytokeratin 14 is a member of the type I keratin family of intermediate filament proteins. It always pairs with the type II keratin K5 and form the primary keratin pair of the keratinocytes of stratified squamous epithelia, including the epidermis as well as mucosal non-keratinizing stratified squamous epithelia. Cytokeratin 14 is strongly expressed in the undifferentiated basal cell layer containing the stem cells and are down-regulated in the differentiating suprabasal cell layers. Otherwise, in the widely well stratified follicular outer root sheath, cytokeratin 14 is uniformly expressed throughout all layers. The expression spectrum of cytokeratin 14 in tumors corresponds well to the patterns in normal epithelia. Thus, most squamous cell carcinomas as well as malignant mesotheliomas strongly express this keratin whereas little, focal, or no expression is found in adenocarcinomas. Cytokeratin 14 may be a useful marker in the differential diagnosis of squamous cell carcinoma from other epithelial tumors. Recent studies also indicate that CK14 expression in breast cancer corresponded with poor clinical outcome and that CK14 may have diagnostic value in the sub-classification of NSCLC.
    产品名:Cytokeratin 14 Antibody / CK14 / KRT14
    货号:orb1716212
    产品中文名:Cytokeratin 14 Antibody / CK14 / KRT14 抗体
    产品详情链接:https://www.biorbyt.com/cytokeratin-14-antibody-ck14-orb1716212.html

    产品细节图片2
     

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    图标文献和实验
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    • Introduction of human 14-3-3 proteins

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    • Simultaneous Quantification of t(14;18) and HPRT Exon 2/3 Deletions in Human Lymphocytes

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