- ￥9932
- Biorbyt
- orb1716142
- 英国
- 2025年07月10日
- IHC-P
- Mouse
- Human
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- 详细信息
- 技术资料
- 抗体名：
Nectin-4 Antibody / PVRL4 抗体
- 抗体英文名：
Nectin-4 Antibody / PVRL4
- 浓度：
详询
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
6-12个月
- 抗原来源：
详询
- 目录编号：
orb1716142
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
MONOCLONAL
- 保存条件：
Aliquot the PVRL4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态：
详询
- 亚型：
Mouse IgG2a, kappa
- 免疫原：
A portion of amino acids 1-200 from the human protein was used as the immunogen for the PVRL4 antibody.
- 规格：
100 ug
Homologous to the poliovirus receptor (PVR/CD155), the nectin immunoglobulin superfamily comprises four known isoforms (-1, -2, -3, and -4). The ectodomain of nectin family members comprises three Ig-like domains (V, C, C). Nectins localize at the adherens junctions (AJ) in epithelial and endothelial cells where they serve as adhesion molecules. Actin-based AJs play a role in mechanical adhesion, cellular morphogenesis and cellular differentiation. Nectin associates with the actin cytoskeleton through its interaction with the actin filament-binding protein afadin. Nectin 4 and afadin co-localize at cadherin-based adherens junctions in MDCKII epithelial cells. Nectin 4 and nectin 3 share a common binding region in the V domain of Nectin 1 and thus compete for Nectin 1 binding. The Nectin 3/4 binding domain maps to the C-C strands of the V domain of Nectin 1. Unlike other nectins, which are more widely expressed, Nectin 4 is mainly expressed in the placenta.
产品名：Nectin-4 Antibody / PVRL4
货号：orb1716142
产品中文名：Nectin-4 Antibody / PVRL4 抗体
产品详情链接：https://www.biorbyt.com/nectin-4-antibody-pvrl4-orb1716142.html
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Nectin-4 Antibody / PVRL4 抗体，orb1716142，Biorbyt
￥9932
