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- 详细信息
- 技术资料
- 抗体名:
GAD65 Antibody / GAD2 抗体
- 抗体英文名:
GAD65 Antibody / GAD2
- 浓度:
详询
- 应用范围:
IHC-P
- 宿主:
Rabbit
- 适应物种:
Human
- 保质期:
6-12个月
- 抗原来源:
详询
- 目录编号:
orb1826337
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
RECOMBINANT
- 保存条件:
Aliquot the GAD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
- 形态:
详询
- 亚型:
Rabbit IgG, kappa
- 免疫原:
A recombinant human GAD2/GAD65 protein fragment (within amino acids 1-200) was used as the immunogen for the GAD2 antibody.
- 规格:
20 ug
This mAb recognizes a protein of 65kDa, which is identified as glutamic acid decarboxylase 2 (GDA2). It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67). GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (Gamma-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes.
产品名:GAD65 Antibody / GAD2
货号:orb1826337
产品中文名:GAD65 Antibody / GAD2 抗体
产品详情链接:https://www.biorbyt.com/gad65-antibody-gad2-orb1826337.html
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GAD65 Antibody / GAD2 抗体,orb1826337,Biorbyt
¥5265










