CD91 Antibody / LRP1 / A2MR 抗体,orb1825674,Biorbyt

CD91 Antibody / LRP1 / A2MR 抗体

,orb1825674,Biorbyt
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  • ¥5265
  • Biorbyt已认证
  • orb1825674
  • 英国
  • 2025年06月02日
  • IHC-P
  • Rabbit
  • Human
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    • 详细信息
    • 技术资料
    • 抗体名

      CD91 Antibody / LRP1 / A2MR 抗体

    • 抗体英文名

      CD91 Antibody / LRP1 / A2MR

    • 浓度

      详询

    • 应用范围

      IHC-P

    • 宿主

      Rabbit

    • 适应物种

      Human

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb1825674

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      RECOMBINANT

    • 保存条件

      Aliquot the recombinant A2MR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

    • 形态

      详询

    • 亚型

      Rabbit IgG, kappa

    • 免疫原

      A recombinant fragment of human protein was used as the immunogen for the recombinant A2MR antibody.

    • 规格

      20 ug

    CD91 Antibody / LRP1 / A2MR 抗体
     

    Members of the LDL receptor gene family, including LDLR (low density lipoprotein receptor), LEP1 (low density lipoprotein related protein), megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and apoER2 are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. LRP1, also designated LRP and Alpha-2-Macroglobulin receptor, is an endocytic receptor that mediates the uptake of at least 15 ligands, including Alpha-2-Macroglobulin and apoE. LRP1 is cleaved into a membrane subunit and an extracellular subunit, which remain non-covalently associated. Proper folding and trafficking of LRP1 is facilitated by the receptor-associated protein (RAP), a molecular chaperone. The uptake of all known ligands through LRP1 can be blocked by RAP, which induces a conformational change in the receptor that renders it unable to bind ligands. LRP1, which is expressed in brain, liver and lung, is also implicated in Alzheimer s disease (AD), as the human LRP gene localizes to a potential AD locus on chromosome 12.
    产品名:CD91 Antibody / LRP1 / A2MR
    货号:orb1825674
    产品中文名:CD91 Antibody / LRP1 / A2MR 抗体
    产品详情链接:https://www.biorbyt.com/cd91-antibody-lrp1-a2mr-orb1825674.html

    CD91 Antibody / LRP1 / A2MR 抗体
     

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