GSTM3 Antibody / Glutathione S-Transferase mu 3 抗体
抗体英文名:
GSTM3 Antibody / Glutathione S-Transferase mu 3
浓度:
详询
应用范围:
IHC-P
宿主:
Mouse
适应物种:
Human
保质期:
6-12个月
抗原来源:
详询
目录编号:
orb1824614
级别:
科研
库存:
99
供应商:
Biorbyt
标记物:
Unconjugated
克隆性:
RECOMBINANT
保存条件:
Aliquot the recombinant GSTM3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
形态:
详询
亚型:
Mouse IgG2b, kappa
免疫原:
Recombinant full-length human GSTM3 protein was used as the immunogen for the recombinant GSTM3 antibody.
规格:
100 ug
Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. GSTM3 protein is selectively expressed in the testis and brain. GSTM3 may also be tumor suppressive in RCC, as low expression has been demonstrated to correlate with RCC risk and poor prognosis in post-op patients.
产品名:GSTM3 Antibody / Glutathione S-Transferase mu 3
货号:orb1824614
产品中文名:GSTM3 Antibody / Glutathione S-Transferase mu 3 抗体
产品详情链接:https://www.biorbyt.com/gstm3-antibody-glutathione-s-orb1824614.html