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文献和实验Activating the NLRP3 Inflammasome Using the Amyloidogenic Peptide IAPP
an inflammasome complex that ultimately cleaves pro-IL-1β and pro-IL-18 into their mature, secreted forms. Here we describe a protocol by which one type of amyloidogenic peptide, islet amyloid polypeptide (IAPP, otherwise known as amylin) can be prepared and used
利钠素家族包括:心房钠尿肽(atrial natriuretic peptide ANP)、脑钠素(brain natriuretic peptide,BNP)、C型利钠素(c-type natriuretic pepdde,CNP)。利钠素家族是肾素-血管紧张素-醛固酮系统的天然拮抗剂,也抑制后叶加压素及交感神经的保钠、保水作用。ANP和BNP两者的作用相似,之前对利钠素与蛛网膜下腔出血(SAH)后的低血钠的关系做过较多的研究,但其与SAH的关系的研究则较少。 心脏收到牵引
Synthesis and Probing of Membrane-bound Peptide Arrays
with amino acid mixtures at randomized positions in the peptide sequences, combine equal aliquots of Fmoc-AA stock solutions for the respective amino acids to be incorporated, dilute with twofold volume of NMP to give 66 mM solutions, and store as described
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