重组人CD137L蛋白|重组人肿瘤坏死因子配体超家族成员 9

产品编号：KMP2413

产品名称：Human CD137L Protein, His Tag

中文名称： 重组人CD137L蛋白

中文全称：重组人肿瘤坏死因子配体超家族成员9蛋白

产品描述：The Human CD137L Protein(KMP2413) is produced in E.coli and the target gene encoding Arg71-Glu254 is expressed with a 6His tag at the C-terminus.

产品别称：肿瘤坏死因子配体超家族成员 9, CD137L, TNFSF9

分子名称：CD137L

预测分子量：20.9 kDa

物种：Human

宿主：E. coli

规格：50ug, 100ug, 200ug

纯化方式：Affinity purification

纯度：>95% as determined by SDS-PAGE

内毒素水平：<1.0 EU/ug determined by the LAL method

缓冲体系：20mM TrisHCl, 150mM NaCl, pH7.4

Uniport:P41273

功能：Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

产品背景：Tumor necrosis factor ligand superfamily member 9(4-1BBL) is single-pass type II membrane protein which is a member of the the tumor necrosis factor family. 4-1BBL is a 254 amino acids cytokine that is expressed in brain, placenta, lung, skeletal muscle and kidney. TNFSF9 has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine may have a role in activation-induced cell death(AICD) and cognate interactions between T-cells and B-cells/macrophages. It has also been shown to be required for the optimal CD8 responses in CD8 T cells, and is thought to be involved in T cell-tumor cell interaction.

保存条件：Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.

运输条件：In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

说明：This product is for research use only.

参考文献：J. Biol. Chem. 285:9202-9210 (2010)