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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
- 英文名:
Human Biotinylated Mesothelin Protein, His Tag, Avi Tag
- 库存:
999
- 供应商:
卡梅德生物科技(天津)有限公司
- 规格:
20ug/100ug
| 规格: | 20ug | 产品价格: | ¥3680.0 |
|---|---|---|---|
| 规格: | 100ug | 产品价格: | ¥9936.0 |
产品编号:KMP2274
产品名称:Human Biotinylated Mesothelin Protein, His Tag, Avi Tag
中文名称: 生物素化重组人Mesothelin蛋白
中文全称:生物素化重组人间皮素蛋白
产品描述:产品描述:The Human Biotinylated Mesothelin Protein(KMP2274) is produced in HEK293 Cells and the target gene encoding Glu296-Ser598 is expressed with a 6His, Avi tag at the C-terminus.
产品别称:间皮素, Megakaryocyte potentiating facto, Mesothelin
分子名称:Mesothelin
预测分子量:33.99 kDa
物种:Human
宿主:HEK293 Cells
规格:50ug, 100ug, 200ug
纯化方式:Affinity purification
纯度:>95% as determined by SDS-PAGE
内毒素水平:<1.0 EU/ug determined by the LAL method
缓冲体系:PBS, pH7.4
Uniport:H3BR90
产品背景:Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa(pleura, pericardium, and peritoneum) and epithelial cells of the trachea, tonsils, fallopian tube, and kidneys. Mesothelin plays an important role in cell survival, proliferation, migration, invasion, tumor progression, and resistance to chemotherapy. The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3(Stat3), inhibit apoptotic signaling and TNF-α-induced apoptosis, and accelerate the G1–S transition. Mesothelin is also found overexpressed in various cancers, including malignant mesothelioma, pancreatic or ovarian carcinoma, sarcomas and in some gastrointestinal or pulmonary carcinomas. As a result of its limited expression in normal tissues, mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
保存条件:Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.
运输条件:In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.
说明:This product is for research use only.
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文献和实验植物源重组人胰岛素生长因子融合蛋白(OsrIGF-1),胰岛素在无血清细胞培养中的最佳替代品。 IGFs家族由两种低分子多肽(IGF-Ⅰ、IGF-Ⅱ)、两类特异性受体及六种结合蛋白组成。IGF-Ⅰ是一个有70个氨基酸的单链碱性蛋白,分子量7649Da,耐热。IGFs的生物学功能不只局限于有丝分裂刺激作用,它们也能诱导分化或促进分化功能的表达。全新推出的植物源重组人类胰岛素生长因子-1融合蛋白(OsrIGF-1)在IGF-1的N末端融合了人血清白蛋白(HSA),HSA作为蛋白质保护剂增加了IGF
为了阐明特定蛋白在细胞胞吞过程的转运机制,有必要精确测定该蛋白质的胞吞速率。视频介绍了一种利用可逆性生物素化来测定多巴胺转运蛋白胞吞速率的方法。0:00 使用可逆性生物素化测量质膜蛋白胞吞速率 0:21 内容订阅 0:56 内容简介 1:20 培养细胞、配制溶液 3:37 蛋白质生物素化、淬火和内化 7:30 蛋白质测定、蛋白质亲和层析及SDS-PAGE电泳检测 9:49 多巴胺转运蛋白的内化作用 11:02 结论 使用可逆性生物素化测量质膜蛋白胞吞速率本视频来源于网络,如有
由武汉大学生命科学院教授、武汉禾元生物科技有限公司董事长杨代常领衔的研发团队从2006年开始进行植物源替代血浆来源的医药蛋白的研究与开发,现已取得突破性进展并已跨入规模化生产的阶段,填补了国际上此项技术空白。相关论文“Large-scale production of functional human serum albumin from transgenic rice seeds ”(利用转基因水稻规模化生产重组人血清白蛋白)于2011年10月31日在线发表于《美国科学院院报
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