重组鼠CD357蛋白|重组鼠肿瘤坏死因子受体超家族成员 18

产品编号：KMP2381

产品名称：Mouse CD357 Protein, Fc Tag, His Tag

中文名称： 重组鼠CD357蛋白

中文全称：重组鼠肿瘤坏死因子受体超家族成员18蛋白

产品描述：产品描述：The Mouse CD357 Protein(KMP2381) is produced in HEK293 Cells and the target gene encoding Ser22-His153 is expressed with a Fc, 6His tag at the C-terminus.

产品别称：肿瘤坏死因子受体超家族成员 18, Tumor necrosis factor receptor superfamily member 18, CD357

分子名称：CD357

预测分子量：15.2 kDa

物种：Mouse

宿主：HEK293 Cells

规格：50ug, 100ug, 200ug

纯化方式：Affinity purification

纯度：>90% as determined by SDS-PAGE

内毒素水平：<1.0 EU/ug determined by the LAL method

缓冲体系：PBS, pH7.4

Uniport:O35714

功能：Receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway (By similarity).

产品背景：Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.

保存条件：Aliquot and store at -20℃ to -80℃. Avoid repeated freezing and thawing cycles.

运输条件：In general, the proteins are provided as lyophilized powder which are shipped at ambient temperature. They are shipped out in dry ice if supplied in liquid form.

说明：This product is for research use only.