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TIA-1 Antibody / T-Cell Intrac

ellular Antigen-1 抗体,orb1716151,Biorbyt
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  • ¥9932
  • Biorbyt已认证
  • orb1716151
  • 英国
  • 2025年07月16日
  • IHC-P
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      TIA-1 Antibody / T-Cell Intracellular Antigen-1 抗体

    • 抗体英文名

      TIA-1 Antibody / T-Cell Intracellular Antigen-1

    • 浓度

      详询

    • 应用范围

      IHC-P

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb1716151

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      RECOMBINANT

    • 保存条件

      Aliquot the T-Cell Intracellular Antigen-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

    • 形态

      详询

    • 亚型

      Mouse IgG1, kappa

    • 免疫原

      Recombinant full-length human protein was used as the immunogen for the T-Cell Intracellular Antigen-1 antibody.

    • 规格

      100 ug

    产品细节图片1
     

    The T cell intracellular antigen 1 (TIA 1) is a 17 kDa cytoplasmic granule associated protein also designated as GMP 17, for granule membrane protein of 17 kDa. The GMP 17/TIA 1 molecule is expressed in cells possessing cytolytic potential and could be involved in the signaling cascade of Fas (CD95) mediated apoptosis. Within hematopoietic cell lines, the rTIA1/1353 monoclonal antibody (mAb) reacts with about 90% of CD16+, 50 60% of CD8+, and less than 10% of CD4+ normal peripheral blood lymphocytes. It reacts with almost all monocytes and granulocytes. This antibody also reacts with CD4+ activated T cell clones, activated NK cell clones, and Con activated thymocytes, but not with B lymphocytes or B cell lines. TIA1 antibody labels cytotoxic T cells and natural killer cells (NK cells). It is also expressed in T-cell lymphoma, large granular lymphocyte (LGL) leukemia and hairy cell leukemia. TIA1 expression in T-cell malignancies may help in differentiating LGL leukemia (high expression) from T-cell lymphocytosis and other T-cell diseases (low expression). TIA1 may also be used to label tumor-infiltrating lymphocytes in the study of immune response to malignancies.
    产品名:TIA-1 Antibody / T-Cell Intracellular Antigen-1
    货号:orb1716151
    产品中文名:TIA-1 Antibody / T-Cell Intracellular Antigen-1 抗体
    产品详情链接:https://www.biorbyt.com/tia-1-antibody-t-cell-intrac-orb1716151.html

    产品细节图片2
     

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