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150ul
货号 | A00716-2 |
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产品名称 | Anti-SNAI1/SNAIL Antibody |
基因名 | SNAI1 |
抗体来源 | Rabbit |
克隆 | Polyclonal |
抗体亚型 | Rabbit IgG |
分子量 | 29KD |
免疫原 | E.coli-derived human SNAIL/SNAI1 recombinant protein (Position: M1-K170). |
内容 | Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500 ug/ml |
产品形态 | Liquid |
保存条件 | 12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
背景资料 | The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition. |
研究类别 | 1. "Entrez Gene: SNAI1 snail homolog 1 (Drosophila)".2. Davidson NE, Sukumar S (September 2005). "Of Snail, mice, and women". Cancer Cell 8(3): 173–4. |
Uniprot ID | SNAI1: O95863 |
推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot. |
为了提供优质的抗体,博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测,以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
应用 | 稀释度* |
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Western blot (WB): | 1:500-2000 |
Flow cytometry (FCM): | 1-3 μg/1x106 cells |
ELISA: | 1:100-1000 |
*稀释度需要用户自己调试,此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
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