Anti-OPN/SPP1 Antibody (Clone#OTI6C12)(MA00634-100ul)

Anti-OPN/SPP1 Antibody (Clone#

OTI6C12)(MA00634-100ul)
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  • ¥1960
  • BOSTER已认证
  • MA00634-100ul
  • 中国
  • 2025年07月14日
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    • 详细信息
    • 技术资料
    • 库存

      大量

    • 供应商

      广州威佳科技有限公司

    • 规格

      100ul

    产品概况

    货号 MA00634
    产品名称 Anti-OPN/SPP1 Antibody (Clone#OTI6C12)
    基因名 SPP1
    抗体来源 Mouse
    克隆 OTI6C12
    抗体亚型 Mouse IgG1
    分子量 33.7KD
    免疫原 Human recombinant protein fragment corresponding to amino acids 17-314 of human SPP1(NP_001035147) produced in E.coli.
    内容 PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
    纯化方式 Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)
    浓度 500 ug/ml
    产品形态 Liquid
    保存条件 Stable for 12 months from date of receipt. Store at -20°C as received.
    背景资料 The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
    研究类别 1. "Entrez Gene: SPP1 secreted phosphoprotein 1". 2. Reinholt FP, Hultenby K, Oldberg A, Heineg rd D (June 1990). "Osteopontin--a possible anchor of osteoclasts to bone". Proc. Natl. Acad. Sci. U.S.A. 87 (12): 4473–5.3. Wang KX, Denhardt DT (2008). "Osteopontin: role in immune regulation and stress responses". Cytokine Growth Factor Rev. 19 (5-6): 333–45.
    Uniprot ID SPP1: P10451

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    [list_product_images]Figure 1. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SPP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SPP1. [/list_product_images]

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