- ￥1960
- BOSTER
- A01485-1-100ul
- 中国
- 2025年07月16日
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- 技术资料
- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
100ul
产品概况
| 货号 | A01485-1 |
|---|---|
| 产品名称 | Anti-BCL11B Antibody |
| 基因名 | BCL11B |
| 抗体来源 | Rabbit |
| 克隆 | Polyclonal |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 130KD |
| 免疫原 | E.coli-derived human Ctip2/BCL11B recombinant protein (Position: K838-S894). |
| 内容 | 500 ug/ml antibody with PBS ，0.02% NaN3 , 1 mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | B-cell lymphoma/leukemia 11B is a protein that in humans is encoded by the BCL11B gene. This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| 研究类别 | 1. Arlotta, P., Molyneaux, B. J., Chen, J., Inoue, J., Kominami, R., Macklis, J. D. Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo. Neuron 45: 207-221, 2005.2. Avram, D., Fields, A., Top, K. P. O., Nevrivy, D. J., Ishmael, J. E., Leid, M. Isolation of a novel family of C2H2 zinc finger proteins implicated in transcriptional repression mediated by chicken ovalbumin upstream promoter transcription factor (COUP-TF) orphan nuclear receptors. J. Biol. Chem. 275: 10315-10322, 2000. 3. Chen, B., Wang, S. S., Hattox, A. M., Rayburn, H., Nelson, S. B., McConnell, S. K. The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex. Proc. Nat. Acad. Sci. 105: 11382-11387, 2008. |
| Uniprot ID | BCL11B: Q9C0K0 |
| 推荐配套的二抗和检测试剂 | Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (EK1002) for Western blot. |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:500-2000 |
| (ELISA)： | 1:100-1000 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Figure 1. Western blot analysis of anti- Ctip2/BCL11B antibody (A01485-1). The sample well of each lane was loaded with 50ug of sample under reducing conditions.
Lane 1: Junkat whole cell lysates,
Lane 2: MOLT-4 whole cell lysates,
Lane 3: rat brain tissue lysates,
Lane 4: mouse brain tissue lysates,
Lane 5: mouse RAW264.7 whole cell lysates,
Lane 6: mouse Ana-1 whole cell lysates.
Use rabbit anti- Ctip2/BCL11B 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for Ctip2/BCL11B at approximately 130KD. The expected band size for Ctip2/BCL11B is at 96KD.[/list_product_images]
Lane 1: Junkat whole cell lysates,
Lane 2: MOLT-4 whole cell lysates,
Lane 3: rat brain tissue lysates,
Lane 4: mouse brain tissue lysates,
Lane 5: mouse RAW264.7 whole cell lysates,
Lane 6: mouse Ana-1 whole cell lysates.
Use rabbit anti- Ctip2/BCL11B 1:1000, probed with a goat anti-rabbit IgG-HRP secondary antibody. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002). A specific band was detected for Ctip2/BCL11B at approximately 130KD. The expected band size for Ctip2/BCL11B is at 96KD.[/list_product_images]
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Anti-Ctip2/BCL11B Antibody(A01485-1-100ul)
￥1960
