- ￥1960
- BOSTER
- M04173-100ul
- 中国
- 2025年07月15日
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- 详细信息
- 技术资料
- 库存：
大量
- 供应商：
广州威佳科技有限公司
- 规格：
100ul
产品概况
| 货号 | M04173 |
|---|---|
| 产品名称 | Anti-ABCE1 Antibody |
| 基因名 | ABCE1 |
| 抗体来源 | Rabbit |
| 克隆 | Monoclonal(Clone:22A86) |
| 抗体亚型 | Rabbit IgG |
| 分子量 | 67KD |
| 免疫原 | A synthesized peptide derived from human ABCE1 |
| 内容 | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.5mg/ml BSA. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500 ug/ml |
| 产品形态 | Liquid |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing. |
| 背景资料 | ATP binding cassette E1 (ABCE1, also RNase L inhibitor) is an ATPase found in humans involved in viral assembly. It is a member of the ATP-binding cassette (ABC) transporters superfamily and OABP subfamily. ABCE1 inhibits the action of ribonuclease L. Ribonuclease L normally binds to 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) and inhibits the interferon-regulated 2-5A/RNase L pathway, which is used by viruses. ABCE1 heterodimerize with ribonuclease L and prevents its interaction with 2-5A, antagonizing the anti-viral properties of ribonuclease L, and allow the virus to synthesize viral proteins. It has also been implicated to have an effect in tumorcell proliferation and antiapoptosis. |
| 研究类别 | 1. Tian, Y; Han, X; Tian, DL (2012). "The biological regulation of ABCE1". IUBMB Life 64 (10): 795–800. |
| Uniprot ID | ABCE1: P61221 |
产品应用细节
为了提供优质的抗体，博士德对每一批抗体都用没有转染过的细胞系和体细胞组织检测，以保证博士德出品的抗体有足够的亲和性足以和对应蛋白天然的表达含量起反应。
| 应用 | 稀释度* |
|---|---|
| Western blot(WB): | 1:500-2000 |
| IHC: | 1:50-1:200 |
| ICC/IF: | 1:50-1:200 |
| IP: | 1:50 |
| FCM: | 1:100 |
*稀释度需要用户自己调试，此处数据仅供参考。
**博士德提供高敏感的二抗和检测试剂盒。详情见相关产品推荐。
产品图片描述
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[list_product_images]Western blot analysis of ABCE1 expression in HeLa cell lysate.[/list_product_images]
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Anti-ABCE1 Antibody(M04173-100ul)
￥1960
